Evidence map›Paper›PMID 41867823›Full record

ArticlebioRxiv : the preprint server for biology2026

DNA Adenine Methylation Clock in Brain Aging and Alzheimer's Disease Progression.

Abdur Rahim, Xiaomei Zhan, Qiyuan Han, Allysha O'Donnell, Angela Jeong, Guru-Swamy Madugundu, Suresh Pujari, Monica Kruk, Xinlong Luo, Ling Li and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Abdur RahimDepartment of Medicinal Chemistry, College of Pharmacy, University of Minnesota-Twin Cities, Minneapolis, MN, 55455, USA.
Xiaomei ZhanDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.
Qiyuan HanDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota-Twin Cities, Minneapolis, MN, 55455, USA.
Allysha O'DonnellDepartment of Chemistry, University of Minnesota-Twin Cities, Minneapolis, MN, 55455, USA.
Angela JeongDepartment of Experimental and Clinical Pharmacology, University of Minnesota-Twin Cities, Minneapolis, MN, 55455, USA.
Guru-Swamy MadugunduDepartment of Medicinal Chemistry, College of Pharmacy, University of Minnesota-Twin Cities, Minneapolis, MN, 55455, USA.
Suresh PujariDepartment of Medicinal Chemistry, College of Pharmacy, University of Minnesota-Twin Cities, Minneapolis, MN, 55455, USA.
Monica KrukDepartment of Medicinal Chemistry, College of Pharmacy, University of Minnesota-Twin Cities, Minneapolis, MN, 55455, USA.
Xinlong LuoDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.
Ling LiDepartment of Experimental and Clinical Pharmacology, University of Minnesota-Twin Cities, Minneapolis, MN, 55455, USA.
Tao P WuDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.
Natalia Y TretyakovaDepartment of Medicinal Chemistry, College of Pharmacy, University of Minnesota-Twin Cities, Minneapolis, MN, 55455, USA.

Funding

Dysregulation of Protein Prenylation in the Pathogenesis of Alzheimer's DiseaseRF1AG056976 · NIA · UNIVERSITY OF MINNESOTA · PI DISTEFANO, MARK D, LI, LING · 2017 to 2017
$1.9M
NIA NIH HHS RF1 AG056976
6 · The paper itself

Abstract

N

Identifiers

PMID41867823
PMCPMC13001325

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.