Evidence map›Paper›PMID 41867947›Full record

ArticleBioactive materials2026

Immunomodulatory effects of biodegradable Mg-Cu-Zn alloy in esophageal cancer.

Lu Chen, Siqi Liao, Xiaohong Wu, Kewen Lai, Yidan Lu, Xingqin Wang, Xuying Zheng, Yu Zhang, Houwen Chen, Qingliang Wang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lu ChenThe Department of Pathology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, PR China.
Siqi LiaoThe Department of Gastroenterology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, PR China.
Xiaohong WuThe Department of Gastroenterology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, PR China.
Kewen LaiThe Department of Gastroenterology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, PR China.
Yidan LuThe Department of Gastroenterology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, PR China.
Xingqin WangInternational Joint Laboratory for Light Alloys (MOE), College of Materials Science and Engineering, Chongqing University, Chongqing, 400044, PR China.
Xuying ZhengInternational Joint Laboratory for Light Alloys (MOE), College of Materials Science and Engineering, Chongqing University, Chongqing, 400044, PR China.
Yu ZhangInternational Joint Laboratory for Light Alloys (MOE), College of Materials Science and Engineering, Chongqing University, Chongqing, 400044, PR China.
Houwen ChenInternational Joint Laboratory for Light Alloys (MOE), College of Materials Science and Engineering, Chongqing University, Chongqing, 400044, PR China.
Qingliang WangThe Department of Pathology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, PR China.
Jian-Feng NieDepartment of Materials Science and Engineering, Monash University, Melbourne, VIC, 3800, Australia.
Zhihang ZhouThe Department of Gastroenterology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biodegradable magnesium and its alloys have demonstrated ability of anti-tumor cells. However, it remains unclear whether they can regulate the tumor's immune-suppressive microenvironment required for effective treatment of tumor-associated esophageal stenosis. In this study, we investigate the effects of pure Mg, Mg-Cu, and Mg-Cu-Zn alloys on tumor growth and regulation of the tumor immune microenvironment. Our

Indexed as

Biodegradable magnesium alloyEsophageal cancerEsophageal stent materialTumor immune microenvironmentTumor inhibition

Identifiers

PMID41867947
PMCPMC12999324

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.