Evidence mapPaperPMID 41868252Full record

ArticleFrontiers in bioinformatics2026

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Neli Fonseca, Amudha Kumari Duraisamy, Zhe Wang, Sriram Somasundharam, Minoosadat Tayebinia, Lucas C de Oliveira, Miao Ma, Jack Turner, Ardan Patwardhan, Gerard J Kleywegt and 2 more

Abstract read
In one paragraph

Article in Frontiers in bioinformatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Neli FonsecaElectron Microscopy Data Bank (EMDB), European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridgeshire, United Kingdom.
Amudha Kumari DuraisamyElectron Microscopy Data Bank (EMDB), European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridgeshire, United Kingdom.
Zhe WangElectron Microscopy Data Bank (EMDB), European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridgeshire, United Kingdom.
Sriram SomasundharamElectron Microscopy Public Image Archive (EMPIAR), European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridgeshire, United Kingdom.
Minoosadat TayebiniaElectron Microscopy Data Bank (EMDB), European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridgeshire, United Kingdom.
Lucas C de OliveiraElectron Microscopy Data Bank (EMDB), European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridgeshire, United Kingdom.
Miao MaElectron Microscopy Data Bank (EMDB), European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridgeshire, United Kingdom.
Jack TurnerElectron Microscopy Data Bank (EMDB), European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridgeshire, United Kingdom.
Ardan PatwardhanCellular Structure and 3D Bioimaging (CS3DB), European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridgeshire, United Kingdom.
Gerard J KleywegtCellular Structure and 3D Bioimaging (CS3DB), European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridgeshire, United Kingdom.
Matthew HartleyElectron Microscopy Public Image Archive (EMPIAR), European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridgeshire, United Kingdom.
Kyle L MorrisElectron Microscopy Data Bank (EMDB), European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridgeshire, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cryogenic sample-electron microscopy (cryoEM) field has generated significant amounts of 3D Electron Microscopy (3DEM) volumetric data and associated metadata, now comprehensively archived in the Electron Microscopy Data Bank (EMDB - www.emdatabank.org) and the Electron Microscopy Public Image Archive (EMPIAR - www.empiar.org). Harnessing the full potential of these resources requires robust, flexible, and publicly accessible tools for data exploration, analysis and retrieval. Here, we present Chart Builder, an interactive web-based platform that enables researchers to create customizable, publication-quality visualizations directly from archival metadata, validation assessments, and cross-reference annotations. Chart Builder integrates the same query-driven and flexible Solr search system as EMDB search, into a user interface with tools to assist users to filter, group, and compare data without programming expertise. It supports multiple chart types (including line, bar, area, scatter (2D and 3D), histogram, bubble, pie, geographic and Venn diagrams) with customizable axes, data series, and statistical operators. Users can apply global filters, define temporal, categorical, or custom query-based axes, and explore multi-dimensional relationships interactively. Chart data-points are linked to their underlying datasets, such that visualisation interaction opens entry-level or archive-level search results for inspection and datasets from charts may be exported in several ways. Findability, accessibility, interoperability and reusability of data are facilitated by these direct access and export mechanisms, including HTML embedding, persistent URL sharing and chart/data download options. By combining interactivity and ease of use with up-to-date access to the EMDB and EMPIAR archive metadata, both computational and experimental communities may explore and visualize current metadata and export to formats for further analysis or as publication-ready figures. Chart Builder promotes community-driven data analysis and empowers users to evaluate trends in the biological 3DEM field. Chart Builder is freely accessible and fully integrated into the EMDB website at https://www.ebi.ac.uk/emdb/statistics/builder/.

Indexed as

cryoEM (cryo-electron microscopy)data repositorydata visualizationFAIR (findable accessible interoperable andreusable) principlesgraph

Identifiers

PMID41868252
PMCPMC13002805

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.