Evidence map›Paper›PMID 41868307›Full record

ArticleRegenerative biomaterials2026

Silk fibroin hydrogel adhesive combined with miR-455 modified framework nucleic acids/ROS-responsive CeO

Chao Ning, Zhichao Zhang, Jiang Wu, Liwei Fu, Yazhe Zheng, Zhixing Zhang, Chuanyang Long, Jianhao Wu, Xiang Sui, Shuyun Liu and 3 more

Abstract read
In one paragraph

Article in Regenerative biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Chao NingInstitute of Orthopedics, Chinese PLA General Hospital, Beijing Key Laboratory of Regenerative Medicine in Orthopedics, Key Laboratory of Musculoskeletal Trauma & War Injuries PLA, Beijing 100853, People's Republic of China.
Zhichao ZhangInstitute of Orthopedics, Chinese PLA General Hospital, Beijing Key Laboratory of Regenerative Medicine in Orthopedics, Key Laboratory of Musculoskeletal Trauma & War Injuries PLA, Beijing 100853, People's Republic of China.
Jiang WuInstitute of Orthopedics, Chinese PLA General Hospital, Beijing Key Laboratory of Regenerative Medicine in Orthopedics, Key Laboratory of Musculoskeletal Trauma & War Injuries PLA, Beijing 100853, People's Republic of China.
Liwei FuInstitute of Orthopedics, Chinese PLA General Hospital, Beijing Key Laboratory of Regenerative Medicine in Orthopedics, Key Laboratory of Musculoskeletal Trauma & War Injuries PLA, Beijing 100853, People's Republic of China.
Yazhe ZhengInstitute of Orthopedics, Chinese PLA General Hospital, Beijing Key Laboratory of Regenerative Medicine in Orthopedics, Key Laboratory of Musculoskeletal Trauma & War Injuries PLA, Beijing 100853, People's Republic of China.
Zhixing ZhangInstitute of Orthopedics, Chinese PLA General Hospital, Beijing Key Laboratory of Regenerative Medicine in Orthopedics, Key Laboratory of Musculoskeletal Trauma & War Injuries PLA, Beijing 100853, People's Republic of China.
Chuanyang LongInstitute of Orthopedics, Chinese PLA General Hospital, Beijing Key Laboratory of Regenerative Medicine in Orthopedics, Key Laboratory of Musculoskeletal Trauma & War Injuries PLA, Beijing 100853, People's Republic of China.
Jianhao WuInstitute of Orthopedics, Chinese PLA General Hospital, Beijing Key Laboratory of Regenerative Medicine in Orthopedics, Key Laboratory of Musculoskeletal Trauma & War Injuries PLA, Beijing 100853, People's Republic of China.
Xiang SuiInstitute of Orthopedics, Chinese PLA General Hospital, Beijing Key Laboratory of Regenerative Medicine in Orthopedics, Key Laboratory of Musculoskeletal Trauma & War Injuries PLA, Beijing 100853, People's Republic of China.
Shuyun LiuInstitute of Orthopedics, Chinese PLA General Hospital, Beijing Key Laboratory of Regenerative Medicine in Orthopedics, Key Laboratory of Musculoskeletal Trauma & War Injuries PLA, Beijing 100853, People's Republic of China.
Tianyu ChenState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, People's Republic of China.
Quanyi GuoInstitute of Orthopedics, Chinese PLA General Hospital, Beijing Key Laboratory of Regenerative Medicine in Orthopedics, Key Laboratory of Musculoskeletal Trauma & War Injuries PLA, Beijing 100853, People's Republic of China.ORCID https://orcid.org/0000-0001-7154-2227
Yunfeng LinState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, People's Republic of China.ORCID https://orcid.org/0000-0003-1224-6561

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The meniscus, a critical fibrocartilaginous structure in the knee joint that cushions load and stabilizes movement, suffers from poor self-healing potential following tears. This impaired repair not only fails to restore joint function but often progresses to osteoarthritis, posing significant clinical challenges. Regrettably, current therapeutic approaches, such as surgical suturing or partial resection, have limited efficacy in achieving functional regeneration of the meniscus. To address these bottlenecks, we developed a multifunctional composite hydrogel system integrating methacrylated silk fibroin (SilMA), cerium dioxide (CeO

Indexed as

CeO2 nanozymesmeniscus tears reconstructionmiRNA-455SilMA hydrogelstFNAs

Identifiers

PMID41868307
PMCPMC13004221

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.