Evidence map›Paper›PMID 41868426›Full record

ArticleFrontiers in aging neuroscience2026

Telomere dysfunction is associated with exacerbated intermittent hypoxia-induced cognitive deficits and nerve damage.

Ying Guo, Yuyang Miao, Jin Tan, Rui Zhao, Duo Jiang, Minghui Zou, Feng Wang, Qiang Zhang

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ying GuoDepartment of Geriatrics, Tianjin Key Laboratory of Elderly Health, Tianjin Geriatrics Institute, Tianjin Medical University General Hospital, Tianjin, China.
Yuyang MiaoDepartment of Geriatrics, Tianjin Key Laboratory of Elderly Health, Tianjin Geriatrics Institute, Tianjin Medical University General Hospital, Tianjin, China.
Jin TanDepartment of Geriatrics, Tianjin Key Laboratory of Elderly Health, Tianjin Geriatrics Institute, Tianjin Medical University General Hospital, Tianjin, China.
Rui ZhaoTianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, China.
Duo JiangDepartment of Genetics, Tianjin Medical University, Tianjin, China.
Minghui ZouDepartment of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.
Feng WangDepartment of Genetics, Tianjin Medical University, Tianjin, China.
Qiang ZhangDepartment of Geriatrics, Tianjin Key Laboratory of Elderly Health, Tianjin Geriatrics Institute, Tianjin Medical University General Hospital, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive impairment associated with obstructive sleep apnea (OSA) is more prevalent and severe in the elderly, possibly due to age-related increases in neuronal susceptibility to intermittent hypoxia (IH). As telomere dysfunction is a key driver of cellular aging, this study aimed to characterize the interaction between telomere dysfunction and IH, and to explore the associated molecular alterations. Using telomere-damaged PC12 cells and G3 Tert

Indexed as

cellular senescencecognitive declineintermittent hypoxianeuronal susceptibilityobstructive sleep apneasenolytics

Identifiers

PMID41868426
PMCPMC13002836

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.