Evidence mapPaperPMID 41868932Full record

ArticleAmerican journal of translational research2026

Relationship between physical activity and cardiovascular disease in adults.

Binbin Hu, Jianyi Li, Mohammad Sarim Sharaf, Farah Abdul Razzak, Favour C Mekowulu, Hafiza Qurat Ul Ain, Danaish Kumar, Inshal Jawed, Mehak Mobin, Syed Ali Farhan Abbas and 1 more

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Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Binbin HuSchool of Education and Arts, Jiujiang Polytechnic University of Science and Technology Jiujiang 332000, China.
Jianyi LiMedical Technology Department, Guizhou Nursing Vocational College Guiyang 550025, Guizhou, China.
Mohammad Sarim SharafSindh Government Hospital Karachi 74700, Sindh, Pakistan.
Farah Abdul RazzakCivil Hospital Karachi 74400, Sindh, Pakistan.
Favour C MekowuluCardiology, Pulmonology, Sleep Medicine Eggenfelden 84307, Bavaria, Germany.
Hafiza Qurat Ul AinCombined Military Hospital Multan 60050, Punjab, Pakistan.
Danaish KumarKarachi Medical and Dental College Karachi 74700, Sindh, Pakistan.
Inshal JawedDow University of Health Sciences Karachi 74200, Sindh, Pakistan.
Mehak MobinMedicare Hospital, Sohail University Karachi 74000, Sindh, Pakistan.
Syed Ali Farhan AbbasJinnah Medical and Dental College Karachi 74400, Sindh, Pakistan.
Wajeeha ImamCombined Military Hospital Multan 60050, Punjab, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCardiovascular disease (CVD) remains a leading cause of morbidity and mortality worldwide, with physical inactivity identified as a critical modifiable risk factor - the association between physical activity levels and cardiometabolic markers warrants further exploration to inform preventive strategies. We investigate the association between physical activity levels and cardiovascular disease in the adult population.

methodsThis retrospective study was conducted at a Tertiary Care Hospital. A total of 554 participants were recruited, including 277 cases diagnosed with CVD and 277 age- and gender-matched controls with no CVD. Physical activity levels were categorized as poor, intermediate, or recommended, based on the weekly activity level. Demographic and clinical data were collected, including Body Mass Index (BMI), blood pressure, lipid profiles, and smoking status.

resultsPhysical inactivity was significantly higher among patients with CVD, with only 17.9% meeting recommended activity levels compared to 82.1% of controls (P<0.001). CVD patients also exhibited significantly higher BMIs, systolic blood pressures, LDL cholesterol levels, and triglyceride levels, as well as lower HDL levels.

conclusionPhysical inactivity is strongly associated with cardiovascular disease and adverse cardiometabolic profiles. Promoting regular physical activity is crucial for reducing cardiovascular risk.

Indexed as

cardiometabolic markersCardiovascular diseasecase-control studyphysical activity

Identifiers

PMID41868932
PMCPMC13000862

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.