Evidence map›Paper›PMID 41869642›Full record

ReviewFrontiers in oncology2026

The role of abnormal amino acid metabolism in the occurrence and development of tumors.

Yuting Zhang, Honglin Chen

Erratum issuedAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Yuting ZhangDepartment of Pharmacy, No. 87 Zhongda Hospital Eastsouth University, Nanjing, Jiangsu, China.
Honglin ChenDepartment of Pharmacy, Jingjiang Traditional Chinese Medicine Hospital, Jingjiang, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The proliferation, migration, and invasion of tumor cells require a large amount of nutrients. Among them, the uptake of amino acids is crucial for most cellular functions, such as protein synthesis and cell growth. Tumor cells obtain a large number of essential amino acids from the environment through unique metabolic pathways and accelerate the synthesis of non-essential amino acids to meet their own needs. This review summarizes the uptake and utilization of amino acids by tumors and their inhibitory effects on immune cells, providing a basis for targeted metabolism in cancer treatment.

Indexed as

amino acidclinicimmunitymetabolismtumor

Identifiers

PMID41869642
PMCPMC13000899

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.