SynthesisFrontiers in psychology2025
Psychosocial issues of neonatal screening in the context of its major expansion: a scoping review.
Synthesis in Frontiers in psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Newborn screening (NBS) programs began in the 1960s in the US and Europe. Systematically offered at birth, these programs enable the early detection of serious, rare, inherited diseases, facilitating timely treatment and improving survival rates. The range of detectable diseases has expanded significantly, with inclusion criteria evolving since the programs' inception. Recent advances in genomics now allow for the detection of all DNA variant, enabling the identification of conditions typically diagnosed later in life and/or for which no effective treatment or preventive interventions are currently available. This expansion raises ethical and psychosocial concerns. Objectives: To explore the psychosocial challenges associated with the expansion of NBS. Methods: Between May 2022 and March 2024, a global scoping review was conducted using three databases and gray literature. PRISMA guidelines were followed, and thematic analysis was applied to synthesize findings. Results: Of 623 articles identified between 1997 and 2024, 68 met inclusion criteria, with nine additional gray literature references, for a total of 77 publications. Most studies originated from North America ( Discussion: These themes were interpreted as higher-level psychosocial constructs: (1) anxious and depressive dimensions of parental responses; (2) Vulnerable Child Syndrome as a construct shaping parental perceptions and caregiving practices; and (3) psychosocial implications of NBS expansion. Parental anxiety and depression were the most studied outcomes, particularly following abnormal or false-positive results. Current professional training and public education appear insufficient given rapid NBS evolution. Viewing NBS as a continuous process within family-healthcare relationships may help mitigate psychosocial risks. Conclusion: Further research in psychology and social sciences is critical to better understand and address psychosocial risks, particularly for late-onset conditions and those without current treatment or prevention options.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.