4-Aminoquinolines block heme iron reactivity and interfere with artemisinin action.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

2 citing papers in PubMed.

1. The Plasmodium heme detoxification protein functions in mitochondrial protein synthesis.Nature communications · 2026
   Article
2. Gain-of-function PfAAT1 mutations compensate for impaired PfCRT function inResearch square · 2026
   Article

Corrections and comments

• Update of
  Quinolines interfere with heme-mediated activation of artemisinins.2025

Authors and funding

2 authors.

Funding

Abstract

Indexed as