Observational studyClinical rheumatology2026
Screening for osteoporosis in patients with inflammatory bowel diseases: a cross-sectional study.
Observational study in Clinical rheumatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
11 authors.
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Abstract
objectiveInflammatory bowel diseases (IBDs) can be associated with bone fragility. We aimed to evaluate bone mineral density (BMD) in patients with IBD.
methodsIn this observational cross-sectional study, we consecutively included patients with IBD without previous diagnosis of low BMD. All patients underwent a standardized evaluation that included laboratory testing, dual-energy X-ray absorptiometry at the lumbar spine and hip to measure BMD and a systematic evaluation by a rheumatologist.
resultsWe included 339 patients with IBD; 64% were women, and the median (interquartile range) age was 42 (32-53) years. BMD assessment revealed osteopenia in 115 (34%) patients and osteoporosis in 40 (12%). Multivariable analysis did not identify variables associated with low BMD. After the evaluation by the rheumatologist, vitamin D supplementation was initiated for 153 (45%) patients, and anti-osteoporosis treatment was started for 24 (7%).
conclusionIn this large cohort study, about 46% of patients with IBD had low BMD. Systematic evaluation led to the initiation of treatments in most patients. Altogether, our results promote multidisciplinary care of patients with IBD. Key points • Low bone mass density occurs in 42% of patients with inflammatory bowel diseases. • Age and female sex are associated with low bone mass density. After the evaluation by the rheumatologist, vitamin D supplementation and anti-osteoporosis treatment were initiated in a large number of patients. • A systematic multidisciplinary assessment for bone fragility could lead to better care of patients with inflammatory bowel disease.
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