Evidence map›Paper›PMID 41870820›Full record

ArticleStress biology2026

The phytohormone indole-3-acetic acid induces quorum sensing signal DSF turnover via a positive feedback biosynthetic loop in the phytopathogen Xanthomonas campestris.

Si-Nan Li, Ming-Lei Zhang, Ying Cui, Lin Li, Chitti Thawai, Lian Jiang, Dong-Lan Tian, Yu-Cheng Gu, Ya-Wen He, Lian Zhou and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stress biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Si-Nan LiState Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Ming-Lei ZhangState Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Ying CuiState Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Lin LiState Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Chitti ThawaiDepartment of Biology, Faculty of Science, King Mongkut's Institute of Technology Ladkrabang, Bangkok, 10520, Thailand.
Lian JiangJiangsu Good Harvest-Wei'en Agrochemical Co. Ltd, Jiangsu, 226200, Qidong, China.
Dong-Lan TianSyngenta Group Co., Ltd, Bochenglu 567, Shanghai, 201201, China.
Yu-Cheng GuSyngenta, Jealott's Hill International Research Center, Berkshire, RE42 6EY, UK.
Ya-Wen HeState Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China. yawenhe@sjtu.edu.cn.
Lian ZhouZhiyuan Innovative Research Center, Student Innovation Center, Zhiyuan College, Shanghai Jiao Tong University, Shanghai, China. lianzhou@sjtu.edu.cn.
Kai SongState Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China. jdsk@sjtu.edu.cn.ORCID http://orcid.org/0009-0003-4624-158X

Funding

National Natural Science Foundation of China 32172355National Natural Science Foundation of China 32502422Startup Fund for Young Faculty at SJTU SFYF at SJTU
6 · The paper itself

Abstract

Indole-3-acetic acid (IAA) accumulates in host plants following infection by Xanthomonas campestris pv. campestris (Xcc), the causal agent of cruciferous black rot. How exposure to IAA affects the invading Xcc remains unclear. Here, we demonstrate that either exogenous addition of IAA or endogenous production of IAA induced turnover of the quorum sensing (QS) signal diffusible signaling factor (DSF) in a RpfB-dependent manner. IAA addition prevented the cytoplasmic and culture pH decline. Transcriptomic analyses revealed four IAA-regulated gene clusters. Specifically, IAA induced the expression of trpB-A, enhancing tryptophan biosynthesis and intracellular IAA accumulation, and thereby establishing a self-reinforcing synthesis loop. IAA upregulated F

Indexed as

Cytoplasmic pHDSFIndole-3-acetic acid (IAA)TryptophanXanthomonas campestris pv. campestris (Xcc)

Identifiers

PMID41870820
PMCPMC13009335

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.