Evidence map›Paper›PMID 41871939›Full record

ArticleCardiovascular research2026

Sodium/glucose cotransporters 2 inhibitors but not other antidiabetic drugs improve frailty in older adults with diabetes and heart failure with preserved ejection fraction.

Pasquale Mone, Marco Ferrone, Francesco Spione, Dimitris Christodoulakis, Francesco Melillo, Antonio Rainone, Domenico Ponticelli, Tullio Tesorio, Marco Di Mauro, Anna Marro and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Pasquale MoneDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Via Francesco De Sanctis, 1-86100, Campobasso, Italy.
Marco FerroneCasa di Cura "Montevergine", Via Mario Malzoni, 5-83013, Mercogliano (Avellino), Italy.
Francesco SpioneCasa di Cura "Montevergine", Via Mario Malzoni, 5-83013, Mercogliano (Avellino), Italy.
Dimitris ChristodoulakisCasa di Cura "Montevergine", Via Mario Malzoni, 5-83013, Mercogliano (Avellino), Italy.
Francesco MelilloCasa di Cura "Montevergine", Via Mario Malzoni, 5-83013, Mercogliano (Avellino), Italy.
Antonio RainoneCasa di Cura "Montevergine", Via Mario Malzoni, 5-83013, Mercogliano (Avellino), Italy.
Domenico PonticelliCasa di Cura "Montevergine", Via Mario Malzoni, 5-83013, Mercogliano (Avellino), Italy.
Tullio TesorioCasa di Cura "Montevergine", Via Mario Malzoni, 5-83013, Mercogliano (Avellino), Italy.
Marco Di MauroLocal Health Authority (ASL) Avellino, Via DegliImbimbo 10/12-83100, Avellino, Italy.
Anna MarroLocal Health Authority (ASL) Avellino, Via DegliImbimbo 10/12-83100, Avellino, Italy.
Gaetano MacinaLocal Health Authority (ASL) Avellino, Via DegliImbimbo 10/12-83100, Avellino, Italy.
Maria MorganteLocal Health Authority (ASL) Avellino, Via DegliImbimbo 10/12-83100, Avellino, Italy.
Germano GuerraDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Via Francesco De Sanctis, 1-86100, Campobasso, Italy.
Gaetano SantulliInternational Translational Research and Medical Education (ITME) Consortium, Joint Academic Research Unit, "Federico II" University, Via Sergio Pansini 5- 80131, Naples, Italy.ORCID 0000-0001-7231-375X

Funding

Beta Cell Intracellular Calcium and DiabetesR01DK123259 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Gaetano Santulli · 2022 to 2023
$840k
American Heart Association 24IPA1268813NHLBI NIH HHS R01 HL146691NHLBI NIH HHS R01-HL146691NHLBI NIH HHS R01-HL159062NHLBI NIH HHS R01-HL164772NIDDK NIH HHS R01-DK033823NIDDK NIH HHS R01 DK123259NIDDK NIH HHS R01-DK123259NIH HHS
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgingCognitive impairmentEndothelial dysfunctionFrailtyGeriatric cardiometabolic healthHFpEFInflammationPhysical functionSGLT2 inhibitorsType 2 diabetes mellitus

Identifiers

PMID41871939
PMCPMC13196867

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.