ArticleThe Journal of international medical research2026
Frailty, socioeconomic factors, and nutritional biomarkers in patients with nondialysis chronic kidney disease: A cross-sectional analysis.
Article in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BackgroundFrailty is an increasingly recognized comorbidity in chronic kidney disease and is associated with adverse outcomes. Although extensively studied in dialysis populations, its prevalence and associated factors in nondialysis chronic kidney disease remain less well-defined. This study aimed to estimate frailty prevalence and identify associated demographic, clinical, and laboratory factors in adults with nondialysis chronic kidney disease.MethodsThis cross-sectional study used data from the National Health and Nutrition Examination Survey 2007-2018, including 9156 adults with nondialysis chronic kidney disease. Frailty status (robust, prefrail, and frail) was assessed using a modified Fried phenotype. Survey-weighted multinomial logistic regression was applied to explore associations with demographic, clinical, and laboratory variables.ResultsThe robust group comprised 30.3% of participants, the prefrail group 67.2%, and the frail group 2.5%. Most participants were in early-stage chronic kidney disease (G1-G2). Frailty was associated with older age, hypertension, cardiovascular disease, and lower education level. Laboratory findings associated with frailty included lower albumin and hemoglobin, higher blood urea nitrogen, lower bilirubin, reduced globulin, decreased lymphocyte count, and elevated monocyte count.ConclusionsFrailty and prefrailty are highly prevalent even in early-stage chronic kidney disease. These findings highlight the need for early screening and integrated care strategies targeting modifiable clinical and sociodemographic factors.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.