Evidence map›Paper›PMID 41872701›Full record

ReviewAllergy2026

Chinese Position Paper on Biologic Therapy for Allergic Rhinitis.

Yuan Zhang, Jingyun Li, Xian Li, Menglin Wang, Xiangli Yang, Li Shi, Zhiwei Cao, Yan Feng, Weiwei Liu, Zhendong Xu and 28 more

Abstract readConsensus StatementReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Allergy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Yuan ZhangDepartment of Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0003-1080-4267
Jingyun LiDepartment of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0001-8066-4648
Xian LiDepartment of Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0003-2948-7660
Menglin WangDepartment of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-3689-1584
Xiangli YangDepartment of Otolaryngology Head and Neck Surgery, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, China.ORCID https://orcid.org/0000-0001-8152-1833
Li ShiDepartment of Otorhinolaryngology Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, Shandong, China.ORCID https://orcid.org/0000-0002-4162-7876
Zhiwei CaoDepartment of Otolaryngology Head and Neck Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.ORCID https://orcid.org/0000-0002-2221-9260
Yan FengDepartment of Otorhinolaryngology Head and Neck Surgery, The First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.ORCID https://orcid.org/0000-0002-1443-0584
Weiwei LiuDepartment of Otolaryngology, Cangzhou Central Hospital, Cangzhou, Hebei, China.ORCID https://orcid.org/0009-0000-8851-250X
Zhendong XuE.N.T. Department, Baotou Central Hospital in Inner Mongolia Autonomous Region, Baotou, Inner Mongolia, China.ORCID https://orcid.org/0009-0005-3688-7103
Ruixia MaDepartment of Otorhinolaryngology Head and Neck Surgery, The First People's Hospital of Yinchuan, Yinchuan, Ningxia Hui Autonomous Region, China.ORCID https://orcid.org/0000-0003-2168-6278
Xiaoping GaoDepartment of Otolaryngology Head and Neck Surgery, General Hospital of Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, China.ORCID https://orcid.org/0009-0005-5490-9134
Wen LiuDepartment of Otorhinolaryngology, Zibo Central Hospital, Zibo, Shandong, China.ORCID https://orcid.org/0009-0003-9807-674X
Jinmei XueDepartment of Otorhinolaryngology, Head and Neck Surgery, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.ORCID https://orcid.org/0000-0002-7428-7812
Xiaoyong RenDepartment of Otolaryngology, Head and Neck Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.ORCID https://orcid.org/0000-0001-6062-2977
Xuezhong LiDepartment of Otorhinolaryngology, Qilu Hospital of Shandong University, NHC Key Laboratory of Otorhinolaryngology (Shandong University), Jinan, Shandong, China.ORCID https://orcid.org/0000-0001-8350-2513
Xicheng SongDepartment of Otorhinolaryngology Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, Shandong, China.ORCID https://orcid.org/0000-0002-9789-1318
Yi YangOtolaryngology Department, Beijing Hospital, National Center of Gerontology, Beijing, China.ORCID https://orcid.org/0009-0000-2548-2542
Fang QuanDepartment of Otolaryngology, Head and Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.ORCID https://orcid.org/0000-0002-9984-9121
Lei ChengDepartment of Otorhinolaryngology, The First Affiliated Hospital With Nanjing Medical University, Nanjing, Jiangsu, China.ORCID https://orcid.org/0000-0001-6541-7702
Weihong JiangDepartment of Otorhinolaryngology, Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID https://orcid.org/0000-0002-3854-8923
Huabin LiAllergy Center, Department of Otolaryngology, Affiliated Eye and ENT Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-2477-2879
Jian LiDepartment of Otorhinolaryngology, Head and Neck Surgery, Guangxi Hospital Division of the First Affiliated Hospital, Sun Yat-Sen University, Nanning, Guangxi Zhuang Autonomous Region, China.ORCID https://orcid.org/0000-0001-6124-6619
Huanhai LiuDepartment of Otolaryngology-Head and Neck Surgery, Second Affiliated Hospital of Naval Medical University, Shanghai, China.ORCID https://orcid.org/0000-0001-9756-7588
Jianfeng LiuDepartment of Otorhinolaryngology-Head and Neck Surgery, China-Japan Friendship Hospital, Beijing, China.ORCID https://orcid.org/0000-0003-4071-6719
Zheng LiuDepartment of Otolaryngology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.ORCID https://orcid.org/0000-0002-4168-6702
Wei LvDepartment of Otolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.ORCID https://orcid.org/0000-0003-0127-8824
Qianhui QiuDepartment of Otolaryngology-Head and Neck Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0001-6335-5173
Xiangdong WangDepartment of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-0409-322X
Yu XuDepartment of Otolaryngology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.ORCID https://orcid.org/0000-0001-7751-6345
Yuanteng XuDepartment of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.ORCID https://orcid.org/0000-0001-9260-1417
Qintai YangDepartment of Otorhinolaryngology-Head and Neck Surgery, Department of Allergy, Naso-Orbital-Maxilla and Skull Base Center, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0003-3377-737X
Yucheng YangDepartment of Otorhinolaryngology, First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID https://orcid.org/0000-0002-2413-2935
Jing YeDepartment of Otorhinolaryngology and Head Neck Surgery, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.ORCID https://orcid.org/0009-0008-9785-5801
Hongmeng YuENT Institute and Department of Otolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-2578-9103
Dongdong ZhuDepartment of Otorhinolaryngology Head and Neck Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China.ORCID https://orcid.org/0000-0002-8495-5626
Chengshuo WangDepartment of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0003-0646-5135
Luo ZhangDepartment of Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-0910-9884

Funding

Beijing Hospitals Authority Clinical Medicine Development ZLRK202303National Key R&D Program of China 2022YFC2504100Natural Science Foundation of China 82025010Natural Science Foundation of China 82371115Natural Science Foundation of China 82471132
6 · The paper itself

Abstract

Allergic rhinitis (AR) is a common, persistent nasal disorder that poses significant public health challenges worldwide. Current treatment options frequently fail to achieve adequate symptom control in a substantial subset of patients. Over the past two decades, biologic therapies that target type 2 inflammatory pathways have been used to treat patients experiencing poorly controlled symptoms, despite standard-of-care (SoC) treatment. Although biological treatment options for AR remain limited worldwide, the recent approval of novel agents, such as stapokibart for seasonal allergic rhinitis (SAR), has accelerated clinical research and development in this field. Evidence for biologic therapy in the management of perennial allergic rhinitis (PAR) is currently sparse. To standardise the use of biologics in AR management and promote their evidence-based application, a multidisciplinary expert panel was convened. This position paper evaluates current evidence regarding the efficacy and safety of biologic agents for AR, incorporating data from both international and regional clinical studies. Here, we provide recommendations on appropriate indications for biologic therapy and emphasise its role in patients with uncontrolled SAR, supporting clinical decision-making and facilitating the integration of biologics into routine practice.

Indexed as

Biological TherapyRhinitis, AllergicBiological ProductsChinaHumansTreatment OutcomeBiological Productsallergic rhinitisbiologicsChinamonoclonal antibodytreatment

Identifiers

PMID41872701
PMCPMC13139808

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.