Evidence mapPaperPMID 41874171Full record

ArticleMicrobiology spectrum2026

Non-viable

Ryosuke Hamashima, Masato Tashiro, Yuichiro Nakano, Tomoyuki Shirahige, Hotaka Namie, Hiromu Yano, Yuya Ito, Masataka Yoshida, Tatsuro Hirayama, Kazuaki Takeda and 14 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Ryosuke HamashimaDepartment of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.ORCID 0009-0002-7589-6684
Masato TashiroDepartment of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.ORCID 0000-0001-7609-7679
Yuichiro NakanoDepartment of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.ORCID 0009-0006-7110-5952
Tomoyuki ShirahigeDepartment of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.ORCID 0000-0003-0458-3090
Hotaka NamieDepartment of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.ORCID 0009-0002-2561-1644
Hiromu YanoDepartment of Tumor Pathology, Graduate School of Health Sciences, Kumamoto University, Kumamoto, Japan.ORCID 0000-0003-3985-0259
Yuya ItoDepartment of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.ORCID 0000-0003-1295-4357
Masataka YoshidaDepartment of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Tatsuro HirayamaDepartment of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.ORCID 0000-0001-8554-3482
Kazuaki TakedaDepartment of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.ORCID 0000-0003-1611-4435
Naoki IwanagaDepartment of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.ORCID 0000-0002-0680-390X
Satoshi KakiuchiInfection Control and Education Center, Department of Infectious Diseases, Nagasaki University Hospital, Nagasaki, Japan.ORCID 0000-0003-4957-3857
Kodai NishiDepartment of Radioisotope Medicine, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan.ORCID 0000-0002-4919-7639
Hong LiuDivision of Infectious Diseases, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.ORCID 0009-0008-3804-9535
Takahiro TakazonoDepartment of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.ORCID 0000-0002-0696-5386
Takeshi TanakaInfectious Diseases Treatment and Prevention Center, Department of Infectious Diseases, Nagasaki University Hospital, Nagasaki, Japan.ORCID 0000-0003-0768-9528
Akira WatanabeDivision of Clinical Research, Medical Mycology Research Center, Chiba University, Chiba, Japan.ORCID 0000-0002-3057-2937
Yoshihiro KomoharaDepartment of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Akitsugu FurumotoInfectious Diseases Experts Training Center, Department of Infectious Diseases, Nagasaki University Hospital, Nagasaki, Japan.ORCID 0000-0001-6656-6929
Katsunori YanagiharaDepartment of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Hiroshi MukaeDepartment of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.ORCID 0000-0002-1429-5706
Scott G FillerDivision of Infectious Diseases, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.ORCID 0000-0001-7278-3700
Koichi TakayamaDepartment of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.ORCID 0000-0002-7723-8960
Koichi IzumikawaDepartment of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.ORCID 0000-0001-9969-824X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An aspergilloma is a fungus ball that forms within a preexisting cavity, most commonly in the lungs but also in the paranasal sinuses. It represents a chronic inflammatory disorder that can persist for months and cause life-threatening hemoptysis. In this study, we hypothesized that the fungus ball is predominantly composed of non-viable hyphae and that chronic inflammation is maintained primarily by host responses to these non-viable elements rather than by ongoing fungal proliferation. To investigate this, we created a murine fungus ball model by implanting heat-killed

Indexed as

angiogenesisanimal modelaspergillomaAspergillus fumigatuschronic inflammationdead hyphaefoam cellfungus balllipid metabolism

Identifiers

PMID41874171
PMCPMC13141880

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.