Evidence map›Paper›PMID 41875155›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

GFAP

Qi Xie, Hui Lu, Xiaoman Wang, Siya Wu, Qian He, Mengqi Yuan, Shuang Zhang, Linlin Hu, Changxiong Gong, Xiaofeng Cheng and 5 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Qi Xie *Department of Neurology, Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China.
Hui Lu *Department of Neurology, Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China.ORCID 0009-0005-7649-8137
Xiaoman Wang *Department of Neurology, Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China.
Siya Wu *Department of Obstetrics and Gynecology, Southwest Hospital of the Third Military Medical University (The First Affiliated Hospital of the Army Medical University), Chongqing 400038, China.
Qian HeDepartment of Neurology, Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China.
Mengqi YuanDepartment of Neurology, Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China.
Shuang ZhangDepartment of Neurology, Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China.ORCID 0009-0003-8779-2185
Linlin HuDepartment of Neurology, Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China.
Changxiong GongDepartment of Neurology, Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China.
Xiaofeng ChengDepartment of Neurology, Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China.
Yiliang FangDepartment of Neurology, Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China.
Zhaoyou MengDepartment of Neurology, Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China.
Yilong WangDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China.
Sen LinDepartment of Neurology, Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China.
Qingwu YangDepartment of Neurology, Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China.ORCID 0009-0005-4604-7335

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ependymal cells in the adult ventricular-subventricular zone are increasingly recognized for functions extending beyond cerebrospinal fluid dynamics; however, their identity and functional specialization remain incompletely understood. While ependymal cells (EP) have been implicated in interactions with the stem cell niche and the vasculature, their role in repair processes following neural injury remains elusive. In this study, we employed region-specific single-cell transcriptomics of the subventricular zone (SVZ) and ipsilesional peri-infarct territory in mice to identify a distinct subpopulation of GFAP

Indexed as

Adaptor Proteins, Signal TransducingBlood-Brain BarrierCalcium-Binding ProteinsEpendymaForkhead Transcription FactorsGlial Fibrillary Acidic ProteinReceptors, NotchAnimalsIntracellular Signaling Peptides and ProteinsMembrane ProteinsMiceSignal TransductionAdaptor Proteins, Signal TransducingCalcium-Binding ProteinsDLL4 protein, mouseForkhead Transcription FactorsGlial Fibrillary Acidic Proteinglial fibrillary astrocytic protein, mouseIntracellular Signaling Peptides and ProteinsMembrane ProteinsReceptors, Notchblood–brain barrier repairependymal cellsFOXF2stroke

Identifiers

PMID41875155
PMCPMC13037844

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.