Evidence map›Paper›PMID 41875868›Full record

ReviewCell reports methods2026

Advances and applications of organ-on-a-chip technology.

Jeong Sik Kong, Jisoo Kim, Jinah Jang, Dong-Woo Cho

Abstract readReview
In one paragraph

Review in Cell reports methods, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Biosensor applications in organ-on-a-chip platforms and disease modeling.Frontiers in bioengineering and biotechnology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeong Sik KongDepartment of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, Gyeongbuk 37673, Republic of Korea; POSTECH-Catholic Biomedical Engineering Institute, POSTECH, Pohang, Kyungbuk 37673, Republic of Korea.
Jisoo KimDepartment of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, Gyeongbuk 37673, Republic of Korea; POSTECH-Catholic Biomedical Engineering Institute, POSTECH, Pohang, Kyungbuk 37673, Republic of Korea.
Jinah JangDepartment of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, Gyeongbuk 37673, Republic of Korea; Department of Creative IT Engineering, Pohang University of Science and Technology (POSTECH), Pohang, Gyeongbuk 37673, Republic of Korea; School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology (POSTECH), Pohang, Gyeongbuk 37673, Republic of Korea. Electronic address: jinahjang@postech.ac.kr.
Dong-Woo ChoDepartment of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, Gyeongbuk 37673, Republic of Korea; POSTECH-Catholic Biomedical Engineering Institute, POSTECH, Pohang, Kyungbuk 37673, Republic of Korea. Electronic address: dwcho@postech.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advancements of the organ-on-a-chip (OOC) technology have been at the forefront of multidisciplinary convergence, blending biology, engineering, and microfabrication. OOC systems recreate human organ functionalities on microfluidic devices and offer more accurate alternatives to traditional testing methods. In this review, we discuss the various fabrication methods such as microfluidics, bioprinting, and injection molding, which are vital for the development of this technology. We further highlight the capability of OOC devices to accurately simulate human organ conditions and their applications in disease modeling, drug testing, and personalized medicine. The integration of OOCs in biological research, including as biosensors for real-time monitoring and in disease modeling, and the use of OOC systems in space research, particularly for studying the effects of microgravity and radiation on human health aboard the International Space Station, are also discussed. This technology shows immense promise for transforming approaches in drug discovery, toxicology, and personalized medicine.

Indexed as

Lab-On-A-Chip DevicesAnimalsBioprintingHumansMicrofluidicsMicrophysiological SystemsPrecision MedicinebioprintingCP: biotechnologydisease modelingdrug testinginjection moldingmicrofluidicsorgan-on-a-chippersonalized medicine

Identifiers

PMID41875868
PMCPMC13030988

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.