Evidence map›Paper›PMID 41876364›Full record

ReviewJournal of immunology (Baltimore, Md. : 1950)2026

Olfactory immunity: defending the neural-mucosal barrier.

Skye Y Tracey, E Ashley Moseman

Abstract readReview
In one paragraph

Review in Journal of immunology (Baltimore, Md. : 1950), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Skye Y TraceyDepartment of Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27710, United States.
E Ashley MosemanDepartment of Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27710, United States.

Funding

Treatment of Primary Amoebic Meningoencephalitis via Modulation of Antibody Effector FunctionsR01NS121067 · NINDS · DUKE UNIVERSITY · PI MOSEMAN, E. ASHLEY · 2021 to 2025
$2.0M
T cell/astrocyte fusions as a novel form of trained immunity to infectionR21NS133561 · NINDS · DUKE UNIVERSITY · PI MOSEMAN, E. ASHLEY · 2023 to 2024
$434k
Defining the molecular and anatomical basis of the blood-olfactory barrier (BOB)R21DC021260 · NIDCD · DUKE UNIVERSITY · PI MOSEMAN, E. ASHLEY · 2023 to 2023
$434k
NIH HHS R01NS121067NIH HHS R21DC021260NIH HHS R21NS133561
6 · The paper itself

Abstract

Olfaction, or the sense of smell, is the ability to detect airborne chemicals that transmit environmental information. Evolutionarily, this sense is essential for finding and judging the safety of food, mediating social relationships, marking territory, and assessing danger. In humans, olfaction is commonly thought to have a unique position in evoking emotional autobiographical experiences. As a critical sense, the olfactory anatomical organization has been highly conserved across mammals. While familiar to everyone, the olfactory system is generally overlooked by immunologists even though it is a mucosal surface with unique connectivity into the central nervous system (CNS). In this review we highlight the basic structures of the olfactory system, pathogens that infect this system, and highlight our expanding knowledge of local immune mechanisms.

Indexed as

Olfactory MucosaSmellAnimalsHumansImmunity, Mucosalneuro-immune interfaceolfactory mucosarespiratory pathogensupper airway immunity

Identifiers

PMID41876364
PMCPMC13046083

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.