ReviewJournal of immunology (Baltimore, Md. : 1950)2026
Vitreoretinal Myeloid Cell Heterogeneity: Diverse Roles in Homeostasis, Immune Surveillance, and Pathophysiology.
Review in Journal of immunology (Baltimore, Md. : 1950), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The retina is a central nervous system tissue with immune-privileged status, protected by the blood-retina barrier and maintained by specialized resident tissue macrophages: microglia, hyalocytes, and perivascular macrophages. These cells exhibit specific ontogeny, spatial localization, and immunologic functions. Each population contributes to homeostasis, phagocytosis, and immunoregulation in their local microenvironment. Microglia are the most abundant immune cells in the retina, and their key functions include vascular and synaptic regulation. Hyalocytes are abundant in the vitreous and at the vitreoretinal interface with key functions including vasoregression and maintenance of a clear visual axis. Perivascular macrophages are present along major venules in the superficial retina and may regulate immune cell transendothelial migration. This review summarizes key vitreoretinal myeloid cell functions, compares/contrasts the relative abundances of antigen presentation machinery and T cell costimulatory molecules, and places these expression levels into the context of immune surveillance in the experimental autoimmune uveitis model.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.