Evidence map›Paper›PMID 41877229›Full record

ArticleJournal of nanobiotechnology2026

Immune-modified exosome vaccine loaded with liver cancer epitope peptides induces potent and specific antitumor immunity.

Shumin Luo, Li Xiao, Fang Xu, Pengpeng Lu, Yiyue Wang, Chuanyun Li, Enhong Xing, Weihua Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shumin LuoBeijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, 100069, China.
Li XiaoJinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China.
Fang XuBeijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, 100069, China.
Pengpeng LuBeijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, 100069, China.
Yiyue WangBeijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, 100069, China.
Chuanyun LiCenter of Liver Transplantation, Beijing Youan Hospital, Capital Medical University, Beijing, 100069, China. lichuany0388@163.com.
Enhong XingAffiliated Hospital of Chengde Medical College, Hebei, 067000, China. xeh001@sina.com.
Weihua LiBeijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing, 100069, China. liweihua@ccmu.edu.cn.

Funding

Beijing Institute of Hepatology Open Project 2025Y-KF-C02Capital Health Development Scientific Research Special Project 2024-2-1152National Natural Science Foundation of China 82274447, 82474425
6 · The paper itself

Abstract

backgroundDendritic cell-derived exosomes (DEXs) are emerging as effective platforms for cancer vaccines due to their capacity to present tumor antigens and regulate immune responses. Here, we developed a multifunctional DEX vaccine (DEX

resultsDEX

conclusionDEX

Indexed as

Cancer VaccinesEpitopesExosomesLiver NeoplasmsPeptidesAnimalsAntigens, NeoplasmCD8-Positive T-LymphocytesCell Line, TumorDendritic CellsFemaleHumansMiceProtein Subunit VaccinesAntigens, NeoplasmCancer VaccinesEpitopesPeptidesProtein Subunit VaccinesCancer vaccineDendritic cell-derived exosomesEpitope peptidesImmunotherapyLiver cancerPD-L1 blockade

Identifiers

PMID41877229
PMCPMC13137727

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.