ArticleFrontiers in medicine2026
The impact of preoperative anticoagulant administration on postoperative coagulation function and blood loss following posterior lumbar interbody fusion: a case-control study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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8 authors.
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Abstract
Background: Currently, there are few reports on the impact of preoperative anticoagulant administration on perioperative coagulation function and blood loss. Therefore, this study observed the effects of preoperative anticoagulant administration on postoperative coagulation function and blood loss in posterior lumbar interbody fusion (PLIF). Methods: A retrospective analysis was conducted on the data of 61 patients who underwent PLIF from October 2021 to March 2023. Patients who used anticoagulants [low-molecular-weight heparin (LMWH) or indobufen] preoperatively were recorded as the observation group ( Results: All surgeries completed successfully with incisions healed in grade A, without DVT occurred. There were no significant differences in surgical time, intraoperative blood loss, postoperative drainage volume, number of blood transfusions, and postoperative hospital stay between the two groups ( Conclusion: The use of anticoagulants before PLIF has no significant effect on postoperative TT, FIB, APTT, and PLT (except for PT), and does not significantly affect blood loss.
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