Evidence map›Paper›PMID 41877990›Full record

ArticleChemical science2026

AccA from

Samantha Firth, William Earl, Denis Thaqi, YoungJin Hong, Charlotte O'Hern, Gemma Luscombe, Dalton Heng Yong Ngu, Zhenyao Luo, Chacko Jobichen, Bostjan Kobe and 2 more

Abstract read
In one paragraph

Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Samantha FirthDepartment of Biosciences, Durham University Durham DH1 3LE UK samantha.j.firth@durham.ac.uk karrera.djoko@durham.ac.uk.ORCID https://orcid.org/0009-0004-1589-6046
William EarlDepartment of Biosciences, Durham University Durham DH1 3LE UK samantha.j.firth@durham.ac.uk karrera.djoko@durham.ac.uk.ORCID https://orcid.org/0009-0004-9061-802X
Denis ThaqiSchool of Chemistry and Molecular Biosciences, The University of Queensland St Lucia QLD 4072 Australia.ORCID https://orcid.org/0000-0001-6208-958X
YoungJin HongDepartment of Biosciences, Durham University Durham DH1 3LE UK samantha.j.firth@durham.ac.uk karrera.djoko@durham.ac.uk.
Charlotte O'HernDepartment of Biosciences, Durham University Durham DH1 3LE UK samantha.j.firth@durham.ac.uk karrera.djoko@durham.ac.uk.ORCID https://orcid.org/0009-0003-1323-1721
Gemma LuscombeDepartment of Biosciences, Durham University Durham DH1 3LE UK samantha.j.firth@durham.ac.uk karrera.djoko@durham.ac.uk.
Dalton Heng Yong NguSchool of Chemistry and Molecular Biosciences, The University of Queensland St Lucia QLD 4072 Australia.ORCID https://orcid.org/0000-0003-1360-9707
Zhenyao LuoSchool of Chemistry and Molecular Biosciences, The University of Queensland St Lucia QLD 4072 Australia.ORCID https://orcid.org/0000-0002-5358-5669
Chacko JobichenSchool of Chemistry and Molecular Biosciences, The University of Queensland St Lucia QLD 4072 Australia.ORCID https://orcid.org/0000-0001-5927-1815
Bostjan KobeSchool of Chemistry and Molecular Biosciences, The University of Queensland St Lucia QLD 4072 Australia.ORCID https://orcid.org/0000-0001-9413-9166
Alastair McEwanSchool of Chemistry and Molecular Biosciences, The University of Queensland St Lucia QLD 4072 Australia.ORCID https://orcid.org/0000-0002-2419-1003
Karrera DjokoDepartment of Biosciences, Durham University Durham DH1 3LE UK samantha.j.firth@durham.ac.uk karrera.djoko@durham.ac.uk.ORCID https://orcid.org/0000-0001-9814-6515

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many bacteria use copper (Cu) to drive key redox reactions and energy metabolism, and they often rely on metallochaperones to deliver Cu to Cu-dependent enzymes. However, why delivery by metallochaperones is needed, and why Cu cannot transfer directly from cellular pools to the target enzymes, is not well understood. Here, we show that the PCu

Identifiers

PMID41877990
PMCPMC13006917

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.