ReviewInternational journal of nanomedicine2026
Nanoscale Approaches to Oro-Dental Tissue Engineering: A Review of Strategies, Composites, and Translational Challenges.
Review in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Antibacterial PET-G/ZnO Composites: A New Approach to Relaxation Splint Materials in the Treatment of Bruxism.Materials (Basel, Switzerland) · 2026Article
- Flower-like ferro-polydopamine nanozymes with peroxidase-like activity for early caries prevention.Frontiers in microbiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral health is vital to human well-being. As a result, various conditions in the oral cavity, including exposure to dentin and edentulous states, lead to diverse oral issues and tissue loss. Although conventional treatments are available, they often have limitations in drug delivery and tissue regeneration. For example, delivered drugs may fail to disrupt bacterial biofilms, thereby increasing resistance within the oral microbiome and weakening immune responses. Additionally, the limited regenerative capacity of dental pulp cells can lead to serious dental emergencies. To address these challenges, innovative nanoarchitectures have been developed to improve their antimicrobial effects and enhance the regenerative potential of oral tissues for oro-dental tissue engineering. This review discusses different nanotechnological strategies for delivery and subsequent tissue engineering in the oral cavity. We first explore concepts to boost regenerative capacity, emphasizing the roles of various nanomaterials that act as antibacterial agents, activate the differentiation of human dental pulp stem cells, and support their integration with soft oral tissues. Beyond nano-therapeutic strategies involving dental implants, we also discuss nanotoxicity issues and remaining challenges in oral health. Finally, we offer perspectives on translating these developments into clinical practice.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.