ArticleJSAMS plus2025
Implementing an online-delivered exercise program for childhood cancer survivors: A hybrid effectiveness-implementation protocol for the MERRIER study.
Article in JSAMS plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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Who cites it
3 citing papers in PubMed.
- Physical Therapy Surveillance in Children with Acute Lymphoblastic Leukemia: A Quality Improvement Initiative.Pediatric reports · 2026Article
- Parent Perspectives on Physical Therapy for Their Child with Acute Lymphoblastic Leukemia:Current oncology (Toronto, Ont.) · 2026Article
- Implementing exercise interventions in pediatric oncology: an expert consensus framework from the FORTEe project.Frontiers in oncology · 2026Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Physical activity levels are low in childhood cancer survivors. Structured physical activity programs are not routinely provided, despite being safe and beneficial for improving physical and psychological health. Innovative health promotion programs delivered online may allow families to receive equitable health support, which may foster survivors to improve their health. Aims: To determine implementation factors of an online exercise program recruited through a community organization, and effectiveness on physical activity levels and self-efficacy for childhood cancer survivors. Methods and analysis: The MERRIER study is a type-1 hybrid effectiveness-implementation. Sixty children (5-18 years old) who have completed treatment for any cancer type will be enrolled between March 2025 and June 2026. Participants will be randomised (stratified by age, cancer type and sex) 1:1 to 3-months multimodal exercise or control group. The intervention group will receive five online consultations with an Accredited Exercise Physiologist to provide behaviour counselling, and prescribe an individualised aerobic, resistance and balance exercise program at low-moderate intensity. The RE-AIM framework will assess reach (e.g. recruitment rate), effectiveness (e.g. physical activity levels), adoption (e.g. qualitative interviews), implementation (e.g. exercise adherence), and maintenance (e.g. self-efficacy at follow-up). Physical function and patient-reported outcomes will be assessed at baseline (T0), post-intervention (T1; week 12) and follow-up (T2, week 24). An Axivity AX3 accelerometer will measure physical activity over five-days at T0/T1. Implications: If effective, we aim to collaborate with community organisations, who are well placed to implement similar programs to childhood cancer survivors. Ethics: The study was approved by The University of Sydney Health Research Ethics Committee (2024/HE000391). Trial registration: ACTRN12624000604505p.
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