Evidence map›Paper›PMID 41879125›Full record

SynthesisJournal of hepato-biliary-pancreatic sciences2026

Incidence and Determinants of Steatotic Liver Disease after Pancreaticoduodenectomy: A Systematic Review and Meta-Analysis.

Ronnakorn Kongsakon, Wasit Wongtrakul, Khemajira Karaketklang, Nonthalee Pausawasdi, Phunchai Charatcharoenwitthaya

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of hepato-biliary-pancreatic sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ronnakorn KongsakonDivision of Gastroenterology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0000-0718-9043
Wasit WongtrakulDivision of Gastroenterology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0001-9732-6354
Khemajira KaraketklangDivision of Gastroenterology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0001-9973-0094
Nonthalee PausawasdiDivision of Gastroenterology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-3737-8555
Phunchai CharatcharoenwitthayaDivision of Gastroenterology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-8334-0267

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSteatotic liver disease (SLD) is an unrecognized complication after pancreaticoduodenectomy (PD) and may affect nutrition and long-term recovery. This meta-analysis estimated the incidence of SLD after PD and identified its clinical and surgical risk factors.

methodsMEDLINE and EMBASE were searched through March 2025 for studies reporting incident SLD after PD. Random-effects models generated pooled incidence and risk estimates. Subgroup, meta-regression, and sensitivity analyses assessed heterogeneity.

resultsForty-seven studies, including 6271 patients (mean age 65.8 ± 3.8 years; 42.9% female), predominantly from Asia, were included. The pooled incidence of SLD after PD was 26.2% (95% CI 22.6-30.3; I

conclusionsApproximately a quarter of patients develop SLD after PD. These findings support longitudinal postoperative liver assessment and early nutrition-focused management in surgical practice.

Indexed as

Fatty LiverPancreaticoduodenectomyPostoperative ComplicationsFemaleHumansIncidencePancreatic NeoplasmsRisk Factorschemotherapypancreatic enzyme replacement therapypancreaticoduodenectomysteatotic liver diseasewhipple procedure

Identifiers

PMID41879125
PMCPMC13397199

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.