Evidence map›Paper›PMID 41881971›Full record

ArticleCell death & disease2026

TPTE, a testis-specific PTEN family member, drives spermatogenesis via PI(4,5)P

Xu Chen, Tianye Wang, Haiqian Wu, Xiangzheng Zhang, Hao Chen, Longsheng Zhang, Yan Zhu, Xingyu Zhang, Bing Wang, Yueshuai Guo and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell death & disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xu ChenDepartment of Histology and Embryology, School of Basic Medical Sciences, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China.
Tianye WangDepartment of Histology and Embryology, School of Basic Medical Sciences, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China.
Haiqian WuDepartment of Histology and Embryology, School of Basic Medical Sciences, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China.
Xiangzheng ZhangDepartment of Histology and Embryology, School of Basic Medical Sciences, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China.ORCID http://orcid.org/0009-0001-8223-151X
Hao ChenDepartment of Histology and Embryology, School of Basic Medical Sciences, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China.
Longsheng ZhangDepartment of Histology and Embryology, School of Basic Medical Sciences, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China.
Yan ZhuDepartment of Histology and Embryology, School of Basic Medical Sciences, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China.
Xingyu ZhangDepartment of Histology and Embryology, School of Basic Medical Sciences, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China.
Bing WangDepartment of Histology and Embryology, School of Basic Medical Sciences, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China.
Yueshuai GuoDepartment of Histology and Embryology, School of Basic Medical Sciences, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China.
Chenghao SituDepartment of Histology and Embryology, School of Basic Medical Sciences, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China.
Ying ZhengDepartment of Histology and Embryology, School of Medicine, Yangzhou University, Yangzhou, China.ORCID http://orcid.org/0000-0002-8852-5738
Yan LiDepartment of Clinical Laboratory, Sir Run Run Hospital, Nanjing Medical University, Nanjing, China. yanli@njmu.edu.cn.ORCID http://orcid.org/0000-0003-0420-4222
Xuejiang GuoDepartment of Histology and Embryology, School of Basic Medical Sciences, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China. guo_xuejiang@njmu.edu.cn.ORCID http://orcid.org/0000-0002-0475-5705
Hui ZhuDepartment of Histology and Embryology, School of Basic Medical Sciences, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China. njzhuhui@njmu.edu.cn.ORCID http://orcid.org/0000-0003-0852-6894

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32300716National Natural Science Foundation of China (National Science Foundation of China) 82221005National Natural Science Foundation of China (National Science Foundation of China) 82271636National Natural Science Foundation of China (National Science Foundation of China) 82371623National Natural Science Foundation of China (National Science Foundation of China) 82401871National Natural Science Foundation of China (National Science Foundation of China) 82530053
6 · The paper itself

Abstract

Phosphatidylinositol(4,5) bisphosphate (PI(4,5)P

Indexed as

Phosphatidylinositol 4,5-DiphosphatePTEN PhosphohydrolaseSpermatogenesisTestisAnimalsAzoospermiaDNA Breaks, Double-StrandedHumansMaleMiceProto-Oncogene Proteins c-aktSignal TransductionSpermatidsSperm MotilityTOR Serine-Threonine KinasesPhosphatidylinositol 4,5-DiphosphateProto-Oncogene Proteins c-aktPTEN PhosphohydrolaseTOR Serine-Threonine Kinases

Identifiers

PMID41881971
PMCPMC13039310

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.