Evidence map›Paper›PMID 41882145›Full record

ArticleScientific reports2026

Dysferlin stabilizes membrane nanodomains of cardiomyocytes after myocardial infarction.

Justus B Wegener, Yannik Zühlke, Carolin Fleischhacker, Justus Marks, Brian Foo, Niklas Bader, Gabriel C Riedemann, Jasper Wedemeyer, Kim-Chi Vu, Ana M Vergel Leon and 10 more

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Justus B Wegener *Department of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 42a, 37075, Göttingen, Germany.
Yannik Zühlke *Department of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 42a, 37075, Göttingen, Germany.
Carolin FleischhackerDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 42a, 37075, Göttingen, Germany.
Justus MarksDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 42a, 37075, Göttingen, Germany.
Brian FooDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 42a, 37075, Göttingen, Germany.
Niklas BaderDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 42a, 37075, Göttingen, Germany.
Gabriel C RiedemannDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 42a, 37075, Göttingen, Germany.
Jasper WedemeyerDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 42a, 37075, Göttingen, Germany.
Kim-Chi VuDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 42a, 37075, Göttingen, Germany.
Ana M Vergel LeonDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 42a, 37075, Göttingen, Germany.
Nora Josefine PaulkeDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 42a, 37075, Göttingen, Germany.
Tobias KohlDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 42a, 37075, Göttingen, Germany.
Henning UrlaubCluster of Excellence "Multiscale Bioimaging from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, Göttingen, Germany.
Constanze SchmidtDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 42a, 37075, Göttingen, Germany.
Gerd HasenfußDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 42a, 37075, Göttingen, Germany.
Tobias MoserCluster of Excellence "Multiscale Bioimaging from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, Göttingen, Germany.
Eva A Rog-ZielinskaInstitute for Experimental Cardiovascular Medicine, Faculty of Medicine, University Heart Center Freiburg-Bad Krozingen, University of Freiburg, Freiburg, Germany.
Christof LenzCluster of Excellence "Multiscale Bioimaging from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, Göttingen, Germany.
Stephan E LehnartDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 42a, 37075, Göttingen, Germany. slehnart@med.uni-goettingen.de.
Sören BrandenburgDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 42a, 37075, Göttingen, Germany. soeren.brandenburg@med.uni-goettingen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite advances in acute care medicine, myocardial infarction (MI) remains a predominant cause of premature death and heart failure. In the MI border zone, cardiomyocytes are exposed to high biomechanical stress that impairs the integrity of the sarcolemmal membrane. Hence, we hypothesized that the Ca

Indexed as

DysferlinMyocardial InfarctionMyocytes, CardiacAnimalsCell MembraneMaleMiceMice, KnockoutProteomicsSarcolemmaVentricular RemodelingDysferlinDysf protein, mouseCardiomyocytesDysferlinMembrane repairMyocardial infarctionProteomics

Identifiers

PMID41882145
PMCPMC13031966

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.