Evidence map›Paper›PMID 41883721›Full record

ArticleFrontiers in psychiatry2026

Risk and resilience: adverse and positive childhood experiences and aggression in adults with and without ADHD.

Johannes Merscher, Wolfgang Retz, Daniel Turner, Petra Retz-Junginger, Steffen Barra

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Johannes MerscherInstitute for Forensic Psychology and Psychiatry, Saarland University, Homburg, Germany.
Wolfgang RetzInstitute for Forensic Psychology and Psychiatry, Saarland University, Homburg, Germany.
Daniel TurnerInstitute for Forensic Psychology and Psychiatry, Saarland University, Homburg, Germany.
Petra Retz-JungingerInstitute for Forensic Psychology and Psychiatry, Saarland University, Homburg, Germany.
Steffen BarraInstitute for Forensic Psychology and Psychiatry, Saarland University, Homburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Identifying risk and protective factors for aggressive behavior is central to effective violence prevention and public safety. In forensic psychiatry, attention-deficit/hyperactivity disorder (ADHD) is common among offenders and is linked to adverse childhood experiences (ACEs) on the one hand and increased aggression on the other hand. Yet, the mechanisms connecting these factors remain insufficiently understood. Evidence on the protective potential of positive childhood experiences (PCEs), particularly when considered alongside ACEs, is also limited. Methods: Guided by resilience theory and a compensatory resilience model, this study analyzed the dynamics among self-reported ACEs, PCEs, and current aggression in an ADHD subsample (n = 154) and a non-ADHD population (n = 205) using hierarchical linear regression analyses. Results: Compared with the non-ADHD group, adults with ADHD reported higher ACE loads, lower PCE scores, and greater aggressive tendencies. In both subsamples, ACEs significantly predicted higher aggression. Among individuals without ADHD, PCEs demonstrated an independent protective association with aggression after adjusting for ACEs and attenuated the ACE-aggression association. This compensatory effect of PCEs was not observed in the ADHD group. Overall, the harmful influence of ACEs on adult aggression appeared to outweigh any mitigating role of PCEs, particularly among individuals with ADHD. Conclusion: ACEs emerged as a robust correlate of current aggression in adults with and without ADHD, underscoring the need to systematically integrate developmental adversity into forensic risk assessment. For individuals with ADHD, violence prevention and public safety strategies may particularly benefit from early prevention and reduction of childhood adversity, trauma-focused interventions where indicated, and evidence-based ADHD treatment to limit the impact of ADHD-related impairments on dynamic aggression-related risk factors. For individuals without ADHD, prevention and rehabilitation efforts may be strengthened by simultaneously reducing ACEs and actively promoting PCEs as resilience-enhancing conditions.

Indexed as

ADHDaggressionchildhood maltreatmentprotective childhood experiencesresiliency theory

Identifiers

PMID41883721
PMCPMC13008880

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.