Evidence map›Paper›PMID 41886105›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Efficacy of guided breathing virtual reality for pain management in patients with cancer undergoing percutaneous transhepatic biliary drainage.

Moonho Kim, Yoonseok Choi, Youngjong Cho, Shin-Tae Kim, Hyeonjun Lee, Seong Hun Park

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Moonho KimDepartment of Hematology and Oncology, University of Ulsan College of Medicine, Gangneung Asan Hospital, Gangneung, South Korea. muno0802@hanmail.net.
Yoonseok ChoiMedical Research Institute, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, South Korea.
Youngjong ChoDepartment of Radiology, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, South Korea.
Shin-Tae KimDepartment of Pulmonology, CHA Gangnam Medical Center, CHA University, Seoul, South Korea.
Hyeonjun LeeSeven Point One, Seoul, South Korea.
Seong Hun ParkDepartment of Pharmaceutical Regulatory Science, Chung-Ang University, Seoul, South Korea.

Funding

Medical Research Promotion Program through the Gangneung Asan Hospital, funded by the Asan Foundation 2024II0009National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) 2021R1G1A101383912
6 · The paper itself

Abstract

purposeThis study aimed to evaluate the feasibility and analgesic potential of a guided breathing virtual reality (VR) intervention for managing pain in patients with cancer undergoing percutaneous transhepatic biliary drainage (PTBD).

methodsIn a randomized, controlled design, patients were assigned to receive either VR with guided deep breathing (VRBG) or conventional VR without breath guidance (VROG). Each group experienced two 7-min VR sessions featuring calming visuals and narration, with the VRBG receiving additional prompts to induce slow, rhythmic breathing.

resultsA total of 45 patients (VRBG, 22; VROG, 23) were enrolled. On the day following PTBD, opioid consumption was significantly lower with VRBG than with VROG (20.25 vs. 56.61 morphine milligram equivalents; P = 0.044). No significant difference was observed in opioid use on the day of the procedure. Patient satisfaction and willingness to reuse VR were comparable between the groups. Mild adverse events were infrequent and self-limiting.

conclusionThe study findings suggest that incorporating structured breathing guidance into VR may enhance its analgesic effect and reduce reliance on opioids after invasive procedures. To our knowledge, this is the first prospective trial to combine VR and guided breathing for PTBD-related pain, and our findings support the potential of guided breathing VR as a non-pharmacological adjunct in cancer pain management. Trial Registration Clinical Research Information Service ( http://cris.nih.go.kr , KCT0006775).

Indexed as

DrainageNeoplasmsPain ManagementVirtual RealityAdultAgedAnalgesics, OpioidFeasibility StudiesFemaleHumansMaleMiddle AgedPatient SatisfactionProspective StudiesRespirationAnalgesics, OpioidDeep breathingPain reliefPercutaneous transhepatic biliary drainageVirtual reality

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.