ArticleHead & neck2026
Malignant Transformation of Oral Epithelial Dysplasia in Southern Finland.
Article in Head & neck, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
backgroundOral epithelial dysplasia (OED) often precedes oral squamous cell carcinoma (OSCC). The aim was to elucidate the risk and time of malignant transformation (MT) of OED.
methodsPatients diagnosed with OED between 2001 and 2011 in Helsinki and Uusimaa, Finland were included. Kaplan-Meier and Cox proportional hazard analysis factors associated with the MT time.
resultsDysplasias of 225 patients (mean age 60.0 years, 51.6% females) were diagnosed as mild (85.8%), moderate (11.6%), or severe (2.7%). MT occurred in 14.7% (51.5% females, 48.5% males) at a median time of 5.5 years (IQR 1.7-12.5 years). MT occurred in 33.3% of severe (n = 6), 34.6% (n = 26) of moderate, and 11.4% (n = 193) of mild dysplasia. Dysplasia severity was associated with an increased risk for MT.
conclusionsMT of OED was 14.7%. The severity of OED is a predictor for MT.
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