Evidence map›Paper›PMID 41888491›Full record

ReviewDiscover oncology2026

The role of mitochondria-associated membranes in tumorigenesis.

Yaqin Zhu, Guoyi Tang, Muya Tang, Baozhen Zhou, Jing Xu, Xiaoli Ma, Ziyu Li, Guichun Liu, Yu Han

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Discover oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. On the Edge of Benefit and Harm: Reactive Oxygen Species in Cancer.International journal of molecular sciences · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yaqin ZhuCollege of Medicine, Xi'an International University, Xi'an, 710077, Shaanxi, China. xaiu25169@xaiu.edu.cn.
Guoyi TangCollege of Medicine, Xi'an International University, Xi'an, 710077, Shaanxi, China.
Muya TangCollege of Medicine, Xi'an International University, Xi'an, 710077, Shaanxi, China.
Baozhen ZhouCollege of Medicine, Xi'an International University, Xi'an, 710077, Shaanxi, China.
Jing XuCollege of Medicine, Xi'an International University, Xi'an, 710077, Shaanxi, China.
Xiaoli MaCollege of Medicine, Xi'an International University, Xi'an, 710077, Shaanxi, China.
Ziyu LiCollege of Medicine, Xi'an International University, Xi'an, 710077, Shaanxi, China.
Guichun LiuCollege of Medicine, Xi'an International University, Xi'an, 710077, Shaanxi, China.
Yu HanCollege of Medicine, Xi'an International University, Xi'an, 710077, Shaanxi, China.

Funding

Initiation Funds for High-level Talents Program of Xi'an International University XAIU202579
6 · The paper itself

Abstract

The structural coupling between organelles is considered central to regulating cellular behavior. While each organelle performs specific functions, contact or structural coupling between them enables highly coordinated functionality. Mitochondria and the endoplasmic reticulum (ER) are vital organelles in eukaryotic cells, serving as the centers of oxidative metabolism and protein synthesis, respectively. Their homeostatic and coordinated interactions are essential for maintaining cellular activity. This review outlines the structure, function, research methodologies, and relationship with tumorigenesis of the mitochondria-associated membranes (MAMs). And discusses the potential of MAMs as therapeutic targets for cancer therapy and drug development.

Indexed as

CancerERMitochondriaMitochondria-associated membranes (MAMs)

Identifiers

PMID41888491
PMCPMC13144476

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.