Observational studyThe Journal of international medical research2026
Association between the Zhejiang University index and metabolic dysfunction-associated fatty liver disease as analyzed in National Health and Nutrition Examination Survey: A retrospective observational study.
Observational study in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
ObjectiveTo evaluate the association between the Zhejiang University index, a composite metabolic indicator, and the risk and severity of metabolic dysfunction-associated fatty liver disease.MethodsThis cross-sectional study utilized data from the National Health and Nutrition Examination Survey conducted from 1999 to 2020. The association between the Zhejiang University index and severity of metabolic dysfunction-associated fatty liver disease was analyzed using multivariable logistic regression, with adjustments made for confounding variables. Subgroup analyses were performed stratified by sex, age, diabetes, and hypertension status. The relationship with alcoholic liver disease was also verified. Multiple sensitivity analyses were conducted, including analyses of data before and after imputation.ResultsThe Zhejiang University index demonstrated a significant positive association with the incidence of metabolic dysfunction-associated fatty liver disease. The odds ratio increased from 1.74 (95% confidence interval: 1.70, 1.77;
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