Evidence map›Paper›PMID 41889411›Full record

ReviewFrontiers in oncology2026

Post-oncologic skin health: cutaneous recovery and rehabilitation after cancer treatments.

Diala Haykal, Anthony Rossi, Delphine Kerob, Brigitte Dréno

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Diala HaykalCentre Laser Palaiseau, Private Practice, Palaiseau, France.
Anthony RossiDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Delphine KerobOncodermatology Department, Saint Louis Hospital, Paris, France.
Brigitte DrénoNantes Université, INSERM, CNRS, Immunology and New Concepts in Immuno Therapy, INCIT, UMR, Nantes, France.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Michael Jason de la Cruz · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Background: Advances in oncology have markedly improved cancer survival, however, chronic cutaneous sequelae induced by chemotherapy, radiotherapy, targeted therapies, and immunotherapies remain common and may persist long after treatment completion. These long-term skin changes, ranging from xerosis and pruritus to pigmentary alterations, fibrosis, and immune-mediated dermatoses, can substantially impair quality of life and functional recovery. Objective: To define the evolving role of dermatology in post-oncologic skin health and to critically synthesize mechanistic and clinical evidence supporting long-term dermatologic rehabilitation strategies. Methods: A structured search of PubMed and MEDLINE (2010-2025) identified clinical and mechanistic studies, consensus guidelines, systematic reviews, and cohort data relevant to post-treatment cutaneous sequelae. Eligible publications included human studies addressing chronic skin changes after cancer therapy or evaluating therapeutic approaches applicable to survivorship dermatology. The search yielded 612 records, of which 148 full-text articles were reviewed and 54 met the inclusion criteria for synthesis. Results: Post-oncologic skin care extends beyond symptomatic management to encompass restoration of epidermal barrier function, mitigation of chronic inflammation, support of the cutaneous microbiome, and improvement of psychosocial well-being. Mechanistic studies highlight persistent structural, immunologic, molecular, and microbial alterations that underline delayed skin recovery. Within this context, photobiomodulation and selective energy-based modalities may support long-term cutaneous resilience, however robust clinical evidence of their benefit is lacking. Conclusion: Dermatologists play a central role in survivorship care by transitioning cutaneous management from symptomatic treatment toward preventive, restorative, and rehabilitative strategies that improve long-term quality of life.

Indexed as

cancer survivorshipcutaneous toxicitiesmicrobiome modulationphotobiomodulationpost-oncologic dermatologyradiation dermatitisregenerative dermatologyskin barrier repair

Identifiers

PMID41889411
PMCPMC13012933

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.