Evidence mapPaperPMID 41889449Full record

ReviewJournal of materials chemistry. C2026

Advances in fluorescence-based point-of-care diagnostics: probes, nanostructures and integrated systems.

Manuela Cedrún-Morales, Enrica Soprano, Giulia Vanoni, Anil Chandra, Helena Iuele, Francesco Colella, Stefania Forciniti, Valentina Onesto, Giuliana Grasso, Giuseppe Gigli and 1 more

Abstract readReview
In one paragraph

Review in Journal of materials chemistry. C, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Manuela Cedrún-MoralesInstitute of Nanotechnology, National Research Council (CNR-NANOTEC) c/o Campus Ecotekne, via Monteroni Lecce 73100 Italy manuelacedrunmorales@cnr.it loretta.delmercato@cnr.it.
Enrica SopranoInstitute of Nanotechnology, National Research Council (CNR-NANOTEC) c/o Campus Ecotekne, via Monteroni Lecce 73100 Italy manuelacedrunmorales@cnr.it loretta.delmercato@cnr.it.
Giulia VanoniInstitute of Nanotechnology, National Research Council (CNR-NANOTEC) c/o Campus Ecotekne, via Monteroni Lecce 73100 Italy manuelacedrunmorales@cnr.it loretta.delmercato@cnr.it.
Anil ChandraDepartment of Biotechnology, School of Life Sciences, Central University of Kashmir Ganderbal 191201 Jammu and Kashmir India.ORCID https://orcid.org/0000-0003-4553-931X
Helena IueleInstitute of Nanotechnology, National Research Council (CNR-NANOTEC) c/o Campus Ecotekne, via Monteroni Lecce 73100 Italy manuelacedrunmorales@cnr.it loretta.delmercato@cnr.it.
Francesco ColellaTecnomed Puglia - Technopole for Precision Medicine (Biotech Lecce Hub) c/o Ecotekne Campus, via Monteroni Lecce 73100 Italy.
Stefania ForcinitiInstitute of Nanotechnology, National Research Council (CNR-NANOTEC) c/o Campus Ecotekne, via Monteroni Lecce 73100 Italy manuelacedrunmorales@cnr.it loretta.delmercato@cnr.it.
Valentina OnestoInstitute of Nanotechnology, National Research Council (CNR-NANOTEC) c/o Campus Ecotekne, via Monteroni Lecce 73100 Italy manuelacedrunmorales@cnr.it loretta.delmercato@cnr.it.
Giuliana GrassoInstitute of Nanotechnology, National Research Council (CNR-NANOTEC) c/o Campus Ecotekne, via Monteroni Lecce 73100 Italy manuelacedrunmorales@cnr.it loretta.delmercato@cnr.it.
Giuseppe GigliInstitute of Nanotechnology, National Research Council (CNR-NANOTEC) c/o Campus Ecotekne, via Monteroni Lecce 73100 Italy manuelacedrunmorales@cnr.it loretta.delmercato@cnr.it.
Loretta L Del MercatoInstitute of Nanotechnology, National Research Council (CNR-NANOTEC) c/o Campus Ecotekne, via Monteroni Lecce 73100 Italy manuelacedrunmorales@cnr.it loretta.delmercato@cnr.it.ORCID https://orcid.org/0000-0001-9733-7088

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorescence-based point-of-care (POC) technologies are rapidly evolving through advances in materials chemistry. This review provides a comprehensive overview of fluorescent molecular probes, proteins, hybrid nanostructures, metal-organic frameworks, silica platforms, carbon dots, and upconverting nanoparticles engineered for portable diagnostics. We highlight fundamental photophysical mechanisms, design strategies for improving brightness, stability, and multiplexing, and the integration of fluorescent materials with microfluidics, wearable interfaces, and smartphone readouts. Current limitations, translational challenges, and emerging trends, including AI-enabled data analysis and next-generation NIR and AIE fluorophores, are discussed. Together, these insights outline how material innovation is driving the next generation of high-performance POC sensing systems.

Identifiers

PMID41889449
PMCPMC13016064

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.