Evidence mapPaperPMID 41889712Full record

ReviewFrontiers in nutrition2026

The value-added challenge of nuts: antioxidant components, functions and applications in nut by-products.

Yingqian Zhou, Yutong Fan, Zihan Yang, Xiaosen Han, Yuhang Li, Ting Liu, Na Sun, Tuanhui Chen, Lei Meng

Abstract readReview
In one paragraph

Review in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yingqian Zhou *School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.
Yutong Fan *School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.
Zihan YangSchool of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.
Xiaosen HanSchool of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.
Yuhang LiSchool of Biotechnology, Jiangnan University, Wuxi, China.
Ting LiuCollege of Biology, Hunan University, Changsha, China.
Na SunSchool of Basic Medical Sciences, North China University of Science and Technology, Tangshan, China.
Tuanhui ChenSchool of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.
Lei MengSchool of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Large quantities of nut processing by products are generated worldwide and remain underutilized despite being rich sources of bioactive compounds. However, comparative integration of their antioxidant compositions and functional relevance is still limited. This review aims to summarize and compare the antioxidant compositions, functional properties, and potential food related applications of major nut by products generated during nut processing, with an emphasis on their relevance as nutritional and functional ingredients. Methods: This review was conducted as a structured narrative synthesis. Relevant literature was retrieved from major academic databases, including Web of Science, Scopus, PubMed, and China National Knowledge Infrastructure (CNKI), covering publications from 2000 to 2025. Earlier foundational studies were also included when necessary to provide historical context. Search terms combined the names of major nut by-products with keywords related to polyphenols, flavonoids, polysaccharides, and antioxidant activity. Studies were selected based on relevance to compositional characterization, antioxidant activity evaluation, mechanistic investigation, and application-related research. Both international and regional peer-reviewed publications were considered to provide a comprehensive overview of current research progress. Results: Nut by products are rich in bioactive compounds such as polyphenols, flavonoids, and polysaccharides, which exhibit strong antioxidant capacity through scavenging reactive oxygen species and modulating oxidative processes. Comparative analysis indicates notable differences in antioxidant efficacy and functional performance among different nut residues. Beyond antioxidant activity, these by products show promising potential in food preservation, freshness maintenance, and natural coloring, as well as nutrition related functionalities including antimicrobial and anti inflammatory effects. Discussion: The findings highlight nut by products as valuable sources of antioxidant compounds for food and nutrition related applications. However, challenges including compositional variability, extraction efficiency, safety evaluation, and standardization remain key barriers to their large scale utilization. Addressing these issues may facilitate the development of value added functional ingredients and support the sustainable utilization of nut processing by products within food systems, thereby promoting circular economy strategies and enhancing the overall value chain of nut industries.

Indexed as

antioxidant capacityfood applicationsfunctional ingredientshuman nutritionnut by-productspolyphenols

Identifiers

PMID41889712
PMCPMC13012995

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.