ArticleFrontiers in nutrition2026
Prognostic value of the AIP index in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The atherogenic index of plasma (AIP) is a recognized predictor of cardiovascular risk, yet its prognostic relevance in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR) remains uncertain. Methods: This single-center retrospective study included 314 severe AS patients who underwent TAVR between 2019 and 2023. Participants were stratified into tertiles by preoperative AIP (Q1 < -0.12; Q2: -0.12 to 0.11; Q3 > 0.11). Outcomes included all-cause mortality, cardiovascular mortality, and major adverse cardiac and cerebrovascular events (MACCE). Multivariable Cox regression and restricted cubic spline (RCS) analyses assessed associations between AIP and clinical endpoints. Results: Over a median follow-up of 29 months (47 all-cause deaths, 34 cardiovascular deaths, and 67 MACCE events), Kaplan-Meier analysis demonstrated progressively poorer outcomes with increasing AIP tertiles (all log-rank Conclusion: Elevated preoperative AIP is independently and linearly associated with increased mortality and MACCE risks in patients with severe AS undergoing TAVR. AIP may serve as a readily available metabolic biomarker providing supplementary prognostic information.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.