Evidence map›Paper›PMID 41890023›Full record

ArticlebioRxiv : the preprint server for biology2026

Quinone reductase 2

Min Chen, Celi Yang, Xin Li, Lingchun Kong, Benjamin H Weekley, Xiaoran Wei, Jennifer C O'Chan, David A Vinson, Bulent Cetin, Aarthi Ramakrishnan and 17 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Min ChenNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Celi YangBeijing Advanced Innovation Center for Structural Biology, MOE Key Laboratory of Protein Sciences, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China.
Xin LiInstitute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen 518132, China.
Lingchun KongNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Benjamin H WeekleyNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Xiaoran WeiNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Jennifer C O'ChanNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
David A VinsonNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Bulent CetinNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Aarthi RamakrishnanNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Li ShenNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Rongsheng ZengInstitute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen 518132, China.
Zheng LiuDepartment of Chemistry, University of Hong Kong, Hong Kong SAR, China.
Juner ZhangDepartment of Chemistry, Princeton, New Jersey 08544, USA.
Kaylee M CappuccioDepartment of Chemistry, Princeton, New Jersey 08544, USA.
Joshua R SokolDepartment of Chemistry, Princeton, New Jersey 08544, USA.
Erdene BaljinnyamBlack Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Ruiqi HuNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Kobi RosenblumSagol Department of Neurobiology, Natural Science Faculty, Center for Gene Manipulation in the Brain, University of Haifa, 3498838, Haifa, Israel.
Henrik MolinaThe Rockefeller University Proteomics Resource Center, The Rockefeller University, New York, NY 10065, USA.
Qingfei ZhengDepartment of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, USA.ORCID 0000-0002-8397-3507
Yael DavidChemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
Samuele G MarroNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.ORCID 0000-0002-9326-6945
Tom W MuirDepartment of Chemistry, Princeton, New Jersey 08544, USA.
Xiang David LiDepartment of Chemistry, University of Hong Kong, Hong Kong SAR, China.
Haitao LiBeijing Advanced Innovation Center for Structural Biology, MOE Key Laboratory of Protein Sciences, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China.ORCID 0000-0001-6741-293X
Ian MazeNash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

Funding

Molecular studies of neural histone monoaminylation in normal and aberrant brain plasticityR01MH116900 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Ian S. Maze · 2019 to 2026
$4.7M
Role of POU4F1 in a Novel Form of AtaxiaR21NS130319 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI MARRO, SAMUELE G., WEBB, BRYN D · 2023 to 2024
$464k
Impact of histone serotonylation domain organization on neurodevelopmentF32MH126534 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHAN, JENNIFER C · 2021 to 2023
$216k
Mechanisms of Histone Serotonylation and MLL5 in Coordinating the Epigenome during NeurodevelopmentF32MH140478 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Benjamin H Weekley · 2025 to 2026
$152k
NIMH NIH HHS F32 MH126534NIMH NIH HHS F32 MH140478NIMH NIH HHS R01 MH116900NINDS NIH HHS R21 NS130319
6 · The paper itself

Abstract

Histone H3 Gln5 serotonylation (H3Q5ser) is a recently described posttranslational modification

Identifiers

PMID41890023
PMCPMC13015520

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.