Evidence map›Paper›PMID 41890115›Full record

ArticlebioRxiv : the preprint server for biology2026

Expanding TheCellMap.org to visualize a genome-scale genetic interaction network for a human cell line.

Ira Horecka, Matej Ušaj, Myra P D Masinas, Henry N Ward, Xiang Zhang, Arshia Z Hassan, Maximilian Billmann, Hannes L Röst, Chad L Myers, Michael Costanzo and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ira HoreckaDepartment of Molecular Genetics, University of Toronto; Toronto ON, M5S 3E1, Canada.
Matej UšajDonnelly Centre, University of Toronto; Toronto ON, M5S 3E1, Canada.
Myra P D MasinasDonnelly Centre, University of Toronto; Toronto ON, M5S 3E1, Canada.
Henry N WardDepartment of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, 55455, USA.
Xiang ZhangDepartment of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, 55455, USA.
Arshia Z HassanDepartment of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, 55455, USA.
Maximilian BillmannDepartment of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, 55455, USA.ORCID 0000-0002-6556-9594
Hannes L RöstDepartment of Molecular Genetics, University of Toronto; Toronto ON, M5S 3E1, Canada.
Chad L MyersDepartment of Computer Science and Engineering, University of Minnesota; Minneapolis, MN, 55455, USA.
Michael CostanzoDonnelly Centre, University of Toronto; Toronto ON, M5S 3E1, Canada.ORCID 0000-0002-7906-2604
Brenda AndrewsDepartment of Molecular Genetics, University of Toronto; Toronto ON, M5S 3E1, Canada.
Charles BooneDepartment of Molecular Genetics, University of Toronto; Toronto ON, M5S 3E1, Canada.

Funding

Methods for large-scale analysis of chemical-genetic interactionsR01HG005084 · NHGRI · UNIVERSITY OF MINNESOTA · PI MYERS, CHAD L · 2010 to 2022
$2.9M
NHGRI NIH HHS R01 HG005084
6 · The paper itself

Abstract

Genetic interaction networks map functional connections between genes and their corresponding pathways and complexes. We previously developed TheCellMap.org as a central repository for storing and analyzing quantitative genetic interaction data produced by genome-scale Synthetic Genetic Array (SGA) analysis in the budding yeast,

Indexed as

genetic interaction databaseGenetic interactionshuman genetic network

Identifiers

PMID41890115
PMCPMC13015506

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.