ArticleFrontiers in neurology
Surgical treatment for cognitive impairment caused by internal jugular vein stenosis: a clinical study of atlas transverse process resection.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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Corrections and comments
- Erratum issued
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10 authors.
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Abstract
Background and objectives: Internal jugular vein (IJV) stenosis, often caused by extrinsic compression from the atlas transverse process, may impair cerebral venous drainage and contribute to cognitive dysfunction, though direct clinical evidence is limited. This study aimed to investigate the correlation between atlas-induced IJV stenosis and cognitive impairment, and to evaluate the effect of surgical decompression on cognitive outcomes. Methods: From January to June 2025, 47 patients with radiologically confirmed IJV stenosis due to atlas transverse process compression were prospectively enrolled. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA). Patients were stratified into higher ( Results: The mean MoCA score for the cohort was 23.21 ± 3.41, indicating cognitive impairment. The higher stenosis group had significantly lower MoCA total scores than the lower group (20.79 ± 0.56 vs. 25.74 ± 0.38, Conclusion: This study indicates that internal jugular vein stenosis caused by atlas transverse process compression is a potentially treatable contributor to cognitive dysfunction. Surgical decompression improved cognitive function, providing direct evidence for the role of the cerebral venous system in cognitive health. Evaluation of patients with cognitive complaints should consider assessment of the head and neck venous system.
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