Evidence map›Paper›PMID 41890799›Full record

ArticleFrontiers in neurology

Surgical treatment for cognitive impairment caused by internal jugular vein stenosis: a clinical study of atlas transverse process resection.

Xupeng Peng, Junpeng Xu, Shuaibin Lu, Haiyang Ma, Sheng Xu, Meng Lv, Zhiqiang Hu, Yuchuan Ding, Xunming Ji, Guangtong Zhu

Erratum issuedAbstract read
In one paragraph

Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Xupeng PengDepartment of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Junpeng XuDepartment of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Shuaibin LuDepartment of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Haiyang MaDepartment of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Sheng XuDepartment of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Meng LvDepartment of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Zhiqiang HuDepartment of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Yuchuan DingDepartment of Neurosurgery, Wayne State University School of Medicine, Detroit, MI, United States.
Xunming JiDepartment of Neurology, Xuanwu Hospital Capital Medical University, Beijing, China.
Guangtong ZhuDepartment of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objectives: Internal jugular vein (IJV) stenosis, often caused by extrinsic compression from the atlas transverse process, may impair cerebral venous drainage and contribute to cognitive dysfunction, though direct clinical evidence is limited. This study aimed to investigate the correlation between atlas-induced IJV stenosis and cognitive impairment, and to evaluate the effect of surgical decompression on cognitive outcomes. Methods: From January to June 2025, 47 patients with radiologically confirmed IJV stenosis due to atlas transverse process compression were prospectively enrolled. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA). Patients were stratified into higher ( Results: The mean MoCA score for the cohort was 23.21 ± 3.41, indicating cognitive impairment. The higher stenosis group had significantly lower MoCA total scores than the lower group (20.79 ± 0.56 vs. 25.74 ± 0.38, Conclusion: This study indicates that internal jugular vein stenosis caused by atlas transverse process compression is a potentially treatable contributor to cognitive dysfunction. Surgical decompression improved cognitive function, providing direct evidence for the role of the cerebral venous system in cognitive health. Evaluation of patients with cognitive complaints should consider assessment of the head and neck venous system.

Indexed as

atlas transverse processcognitive dysfunctioninternal jugular vein stenosismontreal cognitivesurgical decompression

Identifiers

PMID41890799
PMCPMC13012935

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.