Evidence mapPaperPMID 41890891Full record

ReviewFrontiers in pharmacology2026

Gut microbiota and spleen-strengthening and dampness-dispelling therapies in obesity and related metabolic disorders: key mechanisms and therapeutic potential.

Huiyi Peng, Jincheng Jiang, Zhoujin Tan, Ping Jiang

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Huiyi PengThe First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, China.
Jincheng JiangSchool of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China.
Zhoujin TanSchool of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China.
Ping JiangThe First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity, characterized by excessive body fat and systemic low-level inflammation, is closely linked to energy imbalance and gut dysbiosis. Traditional Chinese medicine (TCM) attributes obesity to spleen deficiency and dampness excess, advocating "strengthening the spleen and expelling dampness" as the core treatment strategy. Studies have shown that TCM formulas, botanical drugs, and their active metabolites can significantly enhance the balance of the gut microbiota, correcting lipid and glucose metabolism disorders, and effectively reducing chronic inflammation and oxidative stress. This study summarizes and concludes relevant research, systematically elaborating on the relationships among TCM formulas, botanical drugs, their metabolites for strengthening the spleen and dispelling dampness, and the gut microbiota. Try to elucidate their effects on obesity by regulating the gut microbiota.

Indexed as

energy metabolismgut microbiotaobesitypotential mechanismstrengthening the spleen and dispelling dampnesstraditional Chinese medicine

Identifiers

PMID41890891
PMCPMC13013495

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.