ArticleFrontiers in psychology2026
Mediating effect of self-disclosure between intolerance of uncertainty and existential distress in young and middle-aged patients undergoing maintenance hemodialysis.
Article in Frontiers in psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The proportion of young and middle-aged patients undergoing maintenance hemodialysis (MHD) has increased in recent years. Due to the physical and psychological impacts of the disease, MHD patients are prone to existential distress, which can lead to anxiety, depression, and other psychological issues. This not only severely impairs their quality of life but also imposes a heavy burden on families and society. Objective: To explore the mediating role of self-disclosure between intolerance of uncertainty and existential distress in young and middle-aged MHD patients, and to provide intervention targets for reducing existential distress in this population. Methods: From January 2024 to October 2024, 342 MHD patients treated in the Hemodialysis Center of a tertiary grade A hospital in Nanchong were selected using convenience sampling. A general information questionnaire, the Intolerance of Uncertainty Scale (IUS), the Self-Disclosure Index (SDI), and the Existential Distress Scale (EDS) were used for data collection. Results: The scores of self-disclosure, intolerance of uncertainty, and existential distress in young and middle-aged MHD patients were (38.08 ± 5.97), (45.44 ± 6.10), and (34.39 ± 7.72), respectively. Significant differences in intolerance of uncertainty scores were observed among patients with different genders, age groups, dialysis durations, marital statuses, educational levels, and employment statuses (all Conclusion: Intolerance of uncertainty can directly affect existential distress and indirectly influence it through the mediating role of self-disclosure. Medical staff should not only take measures to reduce patients' intolerance of uncertainty but also promote their active self-disclosure to further lower the level of existential distress.
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