ArticleClinical kidney journal2026
Increased albuminuria is highly prevalent in the general population: prevalence of CKD in the Gutenberg Health Study.
Article in Clinical kidney journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Glomerular Filtration Rate, Albuminuria, and Reported Kidney Disease in Comparison: Results From the German National Cohort (NAKO).Deutsches Arzteblatt international · 2026Observational
- Incidence, risk factors, and mortality impact of chronic kidney disease in middle-aged Finns: a 22-year population-based cohort study.BMC nephrology · 2026Article
- Effectiveness of check-up 35 for detecting targeted diseases in Germany.BMC primary care · 2026Article
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16 authors.
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Abstract
Background: Early diagnosis of chronic kidney disease (CKD) is essential to slow progression and delay or prevent dialysis. However, in the absence of specific symptoms, patients and physicians may remain unaware of the disease for a long period. Here we present an analysis from the Gutenberg Health Study, a prospective longitudinal cohort study, to estimate the prevalence of CKD indicators in the population. Methods: A representative sample of 10 125 individuals underwent extensive medical testing at baseline; 9331 were tested again after 5 years. The estimated glomerular filtration rate (eGFR) was calculated using the Chronic Kidney Disease Epidemiology Collaboration formula with serum creatinine. Urinary albumin:creatinine ratios (UACRs) were determined from spot urine samples. Results: At baseline, 2.5% of subjects had decreased eGFR (<60 ml/min/1.73 m Conclusions: This is the first study to report the longitudinal prevalence of CKD in the population. Chronic increased albuminuria, a sensitive marker of CKD, is highly prevalent in the German population even in the absence of risk factors for kidney disease.
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