ArticleJournal of magnetic resonance imaging : JMRI2026
Intracranial Plaque Characteristics and Extracranial Carotid Plaque-RADS Associated With Stroke Recurrence: A High-Resolution Vessel Wall Imaging Study.
Article in Journal of magnetic resonance imaging : JMRI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Editorial for "Intracranial Plaque Characteristics and Extracranial Carotid Plaque-RADS Associated With Stroke Recurrence: A High-Resolution Vessel Wall Imaging Study".Journal of magnetic resonance imaging : JMRI · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundIn addition to intracranial plaques, extracranial carotid plaques have also been linked to stroke recurrence. However, the association of combined intracranial and extracranial plaque characteristics with stroke recurrence remains unclear. PURPOSE: To evaluate the association between intracranial plaque features and extracranial carotid Plaque Reporting and Data System (Plaque-RADS) with stroke recurrence utilizing high-resolution vessel wall imaging (HR-VWI). STUDY TYPE: Retrospective. POPULATION: The 388 intracranial atherosclerotic ischemic stroke patients (mean age, 57.3 ± 11.5 years, 274 males). FIELD STRENGTH/SEQUENCE: 3T, three-dimensional T1 weighted 3D fast spin echo. ASSESSMENT: HR-VWI was performed in all patients within 7 days of the stroke onset. The imaging features assessed included intracranial plaque characteristics (degree of stenosis, plaque burden, enhancement ratio, remodeling index, and intraplaque hemorrhage [IPH]) and extracranial carotid Plaque-RADS. Patients enrolled between May 2022 and July 2024 were included in the study. All patients were followed for a minimum of 12 months. STATISTICAL TESTS: Mann-Whitney U test or χ
resultsDuring a median follow-up period of 24 months, 55 patients experienced recurrent stroke. Intracranial plaque enhancement ratio (HR, 1.62; 95% CI, 1.11-2.38), IPH (HR, 2.55; 95% CI, 1.47-4.40), and extracranial carotid Plaque-RADS (HR, 2.23; 95% CI, 1.29-3.86) were significantly associated with stroke recurrence. Time-dependent ROC indicated that the maximum AUCs for enhancement ratio, IPH, and Plaque-RADS were 0.75, 0.69, and 0.68, respectively, while the Cox model including all three reached a maximum AUC of 0.79. DATA
conclusionThe combination of intracranial plaque characteristics and extracranial carotid Plaque-RADS can be used to assess ischemic stroke recurrence. EVIDENCE LEVEL: 3. TECHNICAL EFFICACY: Stage 2.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.