Evidence map›Paper›PMID 41892309›Full record

ReviewCells2026

Dual Roles of Ubiquitin-Specific Peptidase 10 (USP10) in Cancer.

Yifei Zhai, Liming Zhou, Manhan Zhao, Qiong Lin

Abstract readReview
In one paragraph

Review in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yifei ZhaiSchool of Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.
Liming ZhouSchool of Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.
Manhan ZhaoSchool of Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.
Qiong LinSchool of Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.

Funding

National Natural Science Foundation of China No.82172942 and No. 81871888 to Q.L.
6 · The paper itself

Abstract

Ubiquitin-specific peptidase 10 (USP10) deubiquitinates multiple signaling proteins in cancer cells. These USP10 substrates contain both tumor suppressors and oncogenic proteins, thus conferring both inhibitory and promoting effects of USP10 on tumorigenesis and progression. This review focuses on the dual roles of USP10 in various cancer types and addresses the association of aberrant USP10 expression with the development of various types of cancers, including hepatocellular carcinoma, lung cancer, breast cancer, prostate cancer, gastric cancer, and acute and chronic myelogenous leukemia. In addition, this review discusses the potential applications of USP10 inhibitors as targeted drugs for cancer therapy.

Indexed as

NeoplasmsUbiquitin ThiolesteraseAnimalsHumansUbiquitinationUbiquitin ThiolesteraseUSP10 protein, humancancerscancer therapydeubiquitinationUSP10USP10 inhibitors

Identifiers

PMID41892309
PMCPMC13025103

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.