Evidence map›Paper›PMID 41892992›Full record

ArticleMuscles (Basel, Switzerland)2026

Degenerative Gastrocnemius Muscle Changes in a Goat Tibial Ostectomy Model Persist 10 Months After Splint Removal.

Benjamin T Baker, Rebecca E Rifkin, Becka Klein, Brittani Lopez, Remigiusz M Grzeskowiak, Elizabeth Croy, Xiaojuan Zhu, Pierre-Yves Mulon, David E Anderson, Dustin L Crouch

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Muscles (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Benjamin T BakerDepartment of Biomedical Engineering, Tickle College of Engineering, University of Tennessee, Knoxville, TN 37996, USA.
Rebecca E RifkinDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996, USA.
Becka KleinDepartment of Biomedical Engineering, Tickle College of Engineering, University of Tennessee, Knoxville, TN 37996, USA.
Brittani LopezDepartment of Biomedical Engineering, Tickle College of Engineering, University of Tennessee, Knoxville, TN 37996, USA.
Remigiusz M GrzeskowiakDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996, USA.
Elizabeth CroyDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996, USA.
Xiaojuan ZhuOffice of Innovative Technologies, University of Tennessee, Knoxville, TN 37996, USA.
Pierre-Yves MulonDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996, USA.ORCID 0000-0001-8722-4370
David E AndersonDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996, USA.ORCID 0000-0003-0745-7591
Dustin L CrouchDepartment of Biomedical Engineering, Tickle College of Engineering, University of Tennessee, Knoxville, TN 37996, USA.

Funding

U.S. Army Medical Research and Materiel Command W81XWH-15-1-0666
6 · The paper itself

Abstract

Major orthopedic limb surgery is often accompanied by external coaptation; the combined effect of these interventions can lead to muscle atrophy and functional impairment. Large animal models, including goats, are commonly used to study orthopedic interventions, yet longitudinal data on muscle changes after such interventions are limited. This study quantified gastrocnemius muscle adaptations in adult Boer-cross goats undergoing a clinically representative unilateral tibial segmental ostectomy and external coaptation protocol. Muscles on the operated side exhibited statistically significant decreases in mass, length, optimal fiber length, and CSA, and increases in nucleus density compared to muscles on the contralateral, non-operated side (

Indexed as

animalatrophycoaptationdisusemusculoskeletalrecovery

Identifiers

PMID41892992
PMCPMC13028890

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.