ArticleJACC. Case reports2026
Association of Antimitochondrial Antibody With Right Atrial Low Voltage and Sick Sinus Syndrome.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Beyond the Sinus Node: Heterogeneous Atrial Substrate in Atrial Fibrillation With Sick Sinus Syndrome.Journal of cardiovascular electrophysiology · 2026Article
- The Role of Antimitochondrial Antibodies in Atrial Cardiomyopathy: Causality or Coincidence?JACC. Case reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntimitochondrial antibodies (AMAs), well known as markers of primary biliary cholangitis, are increasingly recognized in cardiac disease. Their potential association with right atrial (RA) abnormalities and sick sinus syndrome (SSS) remains unclear. CASE SUMMARY: We report three AMA-positive patients with atrial arrhythmia and RA involvement. Two patients demonstrated extensive RA low voltage on electroanatomic mapping, and one patient showed impaired atrial sensing and pacing consistent with SSS. Left ventricular involvement was variable. One patient developed myositis, indicating systemic autoimmune manifestations. DISCUSSION: These cases suggest a potential link between AMA positivity, RA low voltage, and SSS, even in the absence of left ventricular dysfunction. AMA may confer selective RA vulnerability through mitochondrial or immune-mediated pathways, highlighting the need for further investigation.
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Registered trials
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