Evidence map›Paper›PMID 41893642›Full record

ArticleVeterinary sciences2026

Prevalence and Genetic Characterization of Mammalian Orthoreoviruses in Diarrheic Cattle from Guangxi, China.

Haonan Yu, Yuhang Luo, Zhen Liao, Li Fan, Haolan Zhong, Kang Ouyang, Ying Chen, Yeshi Yin, Zuzhang Wei, Yifeng Qin and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Haonan YuLaboratory of Animal Infectious Diseases and Molecular Immunology, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Yuhang LuoLaboratory of Animal Infectious Diseases and Molecular Immunology, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Zhen LiaoLaboratory of Animal Infectious Diseases and Molecular Immunology, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Li FanLaboratory of Animal Infectious Diseases and Molecular Immunology, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Haolan ZhongLaboratory of Animal Infectious Diseases and Molecular Immunology, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Kang OuyangLaboratory of Animal Infectious Diseases and Molecular Immunology, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0000-0003-2082-2362
Ying ChenLaboratory of Animal Infectious Diseases and Molecular Immunology, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Yeshi YinLaboratory of Animal Infectious Diseases and Molecular Immunology, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0000-0001-6866-5525
Zuzhang WeiLaboratory of Animal Infectious Diseases and Molecular Immunology, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0000-0002-6317-2315
Yifeng QinLaboratory of Animal Infectious Diseases and Molecular Immunology, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Qingting DongSchool of Animal Science and Technology, Guangxi Vocational University of Agriculture, Nanning 530009, China.
Yan PanSchool of Animal Science and Technology, Guangxi Vocational University of Agriculture, Nanning 530009, China.
Weijian HuangLaboratory of Animal Infectious Diseases and Molecular Immunology, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0000-0003-3070-0764

Funding

College Students'Innovation and Entrepreneurship Training Program 202310593450Guangxi Key R&D Program AB241484045Guangxi Vocational and Technical University of Agriculture Program XKJ2508Guangxi Vocational and Technical University of Agriculture Program XTKJ2503
6 · The paper itself

Abstract

Mammalian orthoreoviruses (MRVs) infect a wide range of animal hosts, yet epidemiological data from southern China remain limited. Here, we performed regional screening of diarrheic cattle in Guangxi, China, from 2023 to 2025. Using L1-targeted RT-PCR, MRV was detected in 8.4% (15/178) of fecal specimens collected across eight prefectures, with a higher detection rate during the cool (autumn-winter) season (October-March). We obtained two complete S1 segments, assigning one Guangxi strain to MRV1 and the other to MRV3. Phylogenetic analysis of L1 sequences indicated a single local lineage nested within a broader multi-host cluster, which was consistent with segment reassortment. σ1 protein alignment revealed a conserved central/C-terminal scaffold and a variable distal head; notably, the MRV3 σ1 sequence contained an extended ~360-390 aa region compared with MRV1. Overall, these findings provide an epidemiological baseline for Guangxi cattle, integrating detection rate, serotype context, and seasonality to support targeted, seasonally informed surveillance and MRV risk assessment.

Indexed as

bovine diarrheaL1 RT-PCRsegment reassortmenttemporal phylogeneticsσ1 protein

Identifiers

PMID41893642
PMCPMC13030053

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.