SynthesisAge and ageing2026
Effectiveness of physio-cognitive dual-task training on improving global cognition, health-related quality of life, and physical outcomes among older adults with neurocognitive disorders: an umbrella review.
Synthesis in Age and ageing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPhysio-cognitive dual-task training (PCDT), combining physical and cognitive tasks, is a promising approach. However, clarity regarding its effectiveness and evidence credibility remains limited.
objectiveTo evaluate PCDT effectiveness on global cognition, health-related quality of life, and physical outcomes (activities of daily living, gait, balance) in older adults with neurocognitive disorders, assess review quality and evidence certainty, and explore moderator effects.
methodsEight databases and grey literature were searched to 31 December 2024. Two reviewers independently screened, extracted data, and assessed review quality (AMSTAR-2) and evidence certainty (GRADE). Meta-level and study-level meta-analyses were conducted. Subgroup analyses and meta-regression explored moderator effects. PROSPERO: CRD42024622115.
resultsSeventeen reviews with 47 unique meta-analyses involving 81 unique studies were included. Meta-level analyses indicated small significant improvements across outcomes except health-related quality of life. Study-level analyses, correcting for overlapping primary studies, confirmed significant benefits for global cognition and health-related quality of life; however, physical outcome effects were non-significant. Prediction intervals for all outcomes were non-significant. Simultaneous PCDT and higher weekly frequency showed greater benefits. Participants with dementia benefited less than those with mild cognitive impairment. Age was not a significant moderator. Most reviews were low or critically low quality, and evidence certainty was low.
conclusionsPCDT is potentially associated with improvements in cognitive, physical, and quality-of-life outcomes among older adults with neurocognitive disorders. However, prediction intervals suggest effectiveness uncertainty, and heavy sample weighting toward prodromal stages warrants caution. PCDT may not be indicated for cognitive improvement in established dementia. High-quality reviews are urgently needed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.