Evidence map›Paper›PMID 41895832›Full record

ArticleAsia Pacific journal of clinical nutrition2026

Association between dietary fat intake and fatty acid profiles and hyperuricemia among Chinese adults: Results from the China Health and Nutrition Survey.

Pengfeng Qu, Yingying Jiao, Liusen Wang, Weiyi Li, Hongru Jiang, Jiguo Zhang, Huijun Wang, Bing Zhang, Junhua Han, Aidong Liu and 1 more

Erratum issuedAbstract read
In one paragraph

Article in Asia Pacific journal of clinical nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Pengfeng QuOffice of National Nutrition Plan, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Yingying JiaoOffice of National Nutrition Plan, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Liusen WangOffice of National Nutrition Plan, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Weiyi LiOffice of National Nutrition Plan, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Hongru JiangOffice of National Nutrition Plan, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Jiguo ZhangOffice of National Nutrition Plan, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Huijun WangOffice of National Nutrition Plan, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Bing ZhangOffice of National Nutrition Plan, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Junhua HanChinese Nutrition Society, Beijing, China.
Aidong LiuOffice of National Nutrition Plan, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China. Email: liuad@ninh.chinacdc.cn.
Zhihong WangOffice of National Nutrition Plan, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China. Email: wangzh@ninh.chinacdc.cn.

Funding

Public Health Emergency Project, National Financial Projects No.131031107000210002Study of Diet and Nutrition Assessment and Intervention Technology, National Key R&D Program No.2020YFC2006300
6 · The paper itself

Abstract

BACKGROUND AND

objectivesDiet is a modifiable factor influencing serum uric acid levels, but evidence on the associations between dietary fat composition and hyperuricemia (HUA) remains limited. This study examined the relationships between the proportion of energy from total fat and specific dietary fatty acids and the risk of HUA among Chinese adults. METHODS AND STUDY

designData were obtained from adults who participated in at least two follow‑up waves of the China Health and Nutrition Survey (CHNS) in 2009, 2015, and 2018. Associations and dose-response relationships were assessed using multivariate Cox proportional hazards and restricted cubic spline (RCS) models.

resultsDuring a mean follow‑up of 6.05 years among 2,722 participants, the prevalence of HUA was 10.2% (men: 14.1%; women: 7.76%). In women, energy from saturated fatty acids (SFAs) in the fourth quintile (7.88%) and from monounsaturated fatty acids (MUFAs) in the third quintile (9.97%) was positively associated with HUA (HR = 2.19, 95% CI 1.19-4.05; HR = 2.14, 95% CI 1.21-3.79), whereas polyunsaturated fatty acids (PUFAs) in the third quintile (6.88%) were negatively associated (HR = 0.41, 95% CI 0.22-0.78). RCS analyses showed J‑shaped and U‑shaped as-sociations in men between total fat (37.9%, 95% CI 11.0-40.3) and PUFAs energy ratio (9.60%, 95% CI 2.25-10.7) with HUA, respectively, and an L‑shaped association in women for PUFAs energy ratio (6.25%, 95% CI 5.54-9.42).

conclusionsThese findings suggest sex‑specific, non‑linear relationships be-tween total fat and different fatty acid intakes and HUA risk. Men should consider moderating total fat intake, while women should limit SFAs and moderately increase PUFAs to help reduce HUA risk.

Indexed as

Dietary FatsFatty AcidsHyperuricemiaAdultChinaEast Asian PeopleFemaleHumansMaleMiddle AgedNutrition SurveysDietary FatsFatty Acidsfatshyperuricemiamonounsaturated fatty acidspolyunsaturated fatty acidssaturated fatty acids

Identifiers

PMID41895832
PMCPMC13012835

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.