ArticleDiabetologia2026
Post-OGTT hypoglycaemia in newly diagnosed type 2 diabetes: frequency, characteristics and cluster assignment.
Article in Diabetologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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Who cites it
1 citing paper in PubMed.
- Association of Post-Oral Glucose Tolerance Test Hypoglycaemia With Clinical Features, Incident Diabetes and Mortality in the Di@bet.es Cohort.Diabetes, obesity & metabolism · 2026Article
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Authors and funding
7 authors.
Funding
Abstract
aims/hypothesisThe aim of this study was to assess the frequency and metabolic characteristics of post-OGTT hypoglycaemia during an OGTT in individuals newly diagnosed with type 2 diabetes.
methodsWe analysed 97 extended (180 min) 75 g OGTTs from individuals newly diagnosed with type 2 diabetes. Glucose, insulin and C-peptide were measured at fasting and post-challenge time points. Insulin sensitivity was assessed using the oral glucose insulin sensitivity (OGIS) index and beta cell function was measured using the insulinogenic index (IGI) and Stumvoll's second-phase index. All participants were assigned to the Ahlqvist diabetes clusters.
resultsPost-OGTT hypoglycaemia (glucose ≤3.9 mmol/l at 180 min) occurred in 8.2% of the OGTTs analysed. Compared with individuals without hypoglycaemia, individuals with post-OGTT hypoglycaemia had a significantly lower BMI and higher insulin sensitivity, without differences in beta cell function. All individuals with hypoglycaemia were assigned to the mild obesity- or age-related diabetes Ahlqvist clusters. CONCLUSIONS/
interpretationPost-OGTT hypoglycaemia is present in a subset of individuals newly diagnosed with type 2 diabetes and is associated with higher insulin sensitivity.
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